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Role of neural crest in congenital heart disease.

1990; Lippincott Williams & Wilkins; Volume: 82; Issue: 2 Linguagem: Inglês

10.1161/01.cir.82.2.332

1524-4539

Michael Kirby, Karen L. Waldo,

Congenital heart defects research

HomeCirculationVol. 82, No. 2Role of neural crest in congenital heart disease. Free AccessAbstractPDF/EPUBAboutView PDFSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toFree AccessAbstractPDF/EPUBRole of neural crest in congenital heart disease. M L Kirby and K L Waldo M L KirbyM L Kirby Department of Anatomy, Medical College of Georgia, Augusta 30912-2000. and K L WaldoK L Waldo Department of Anatomy, Medical College of Georgia, Augusta 30912-2000. Originally published1 Aug 1990https://doi.org/10.1161/01.CIR.82.2.332Circulation. 1990;82:332–340 Previous Back to top Next FiguresReferencesRelatedDetailsCited By Van Praagh R (2022) Embryology and Etiology Congenital Heart Disease, 10.1016/B978-1-56053-368-9.00002-0, (14-58), . 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Gandhi S, Ezin M and Bronner M (2020) Reprogramming Axial Level Identity to Rescue Neural-Crest-Related Congenital Heart Defects, Developmental Cell, 10.1016/j.devcel.2020.04.005, 53:3, (300-315.e4), Online publication date: 1-May-2020. Wittig J and Münsterberg A (2019) The Chicken as a Model Organism to Study Heart Development, Cold Spring Harbor Perspectives in Biology, 10.1101/cshperspect.a037218, 12:8, (a037218), Online publication date: 1-Aug-2020. Sergi C (2020) Endocrine System Pathology of Childhood and Adolescence, 10.1007/978-3-662-59169-7_11, (933-1001), . Cerrizuela S, Vega‐Lopez G and Aybar M (2020) The role of teratogens in neural crest development, Birth Defects Research, 10.1002/bdr2.1644, 112:8, (584-632), Online publication date: 1-May-2020. Bois J and Connolly H (2019) Non‐ M arfan Aortopathies and the Pregnant Patient Cardiac Problems in Pregnancy, 4th Edition, 10.1002/9781119409861.ch20, (305-318), Online publication date: 26-Aug-2019. Kvasilova A, Gregorovicova M, Kundrat M and Sedmera D (2018) HNK‐1 in Morphological Study of Development of the Cardiac Conduction System in Selected Groups of Sauropsida, The Anatomical Record, 10.1002/ar.23925, 302:1, (69-82), Online publication date: 1-Jan-2019. Ikeno Y, Koide Y, Matsueda T, Yamanaka K, Inoue T, Ishihara S, Nakayama S, Tanaka H, Sugimoto K and Okita Y (2018) Anatomical variations of aortic arch vessels in Japanese patients with aortic arch disease, General Thoracic and Cardiovascular Surgery, 10.1007/s11748-018-1001-3, 67:2, (219-226), Online publication date: 1-Feb-2019. Gittenberger-de Groot A, Jongbloed M, Poelmann R and Bartelings M (2019) Structural Heart Disease: Embryology Fetal Therapy, 10.1017/9781108564434.013, (110-122) Findlay R, Thompson O, Ziganshin B and Elefteriades J (2018) Guilt by Association New Approaches to Aortic Diseases from Valve to Abdominal Bifurcation, 10.1016/B978-0-12-809979-7.00010-9, (107-118), . Vojacek J, Zacek P, Dominik J and Holubec T (2018) Congenital Anomalies of the Aortic Valve Aortic Regurgitation, 10.1007/978-3-319-74213-7_6, (43-66), . Nakae R, Fujiki Y, Yokobori S, Naoe Y and Yokota H (2017) Subarachnoid Aneurysmal Hemorrhage Associated with Coarctation of the Aorta: Case Report and Review of the Literature, Journal of Nippon Medical School, 10.1272/jnms.84.186, 84:4, (186-192), . Klena N, Gibbs B and Lo C (2017) Cilia and Ciliopathies in Congenital Heart Disease, Cold Spring Harbor Perspectives in Biology, 10.1101/cshperspect.a028266, 9:8, (a028266), Online publication date: 1-Aug-2017. Kalev-Altman R, Monsonego-Ornan E and Sela-Donenfeld D (2017) The Role of Matrix Metalloproteinase-2 and Metalloproteinase-9 in Embryonic Neural Crest Cells and Their Derivatives Proteases in Physiology and Pathology, 10.1007/978-981-10-2513-6_2, (27-48), . Jongbloed M, Poelmann R and Gittenberger-de Groot A (2017) Embryology The Complete Reference for Scimitar Syndrome, 10.1016/B978-0-12-810406-4.00003-5, (17-43), . Niwa K (2017) Pathological Background Aortopathy, 10.1007/978-4-431-56071-5_2, (15-30), . Ma P, Gu S, Karunamuni G, Jenkins M, Watanabe M and Rollins A (2016) Cardiac neural crest ablation results in early endocardial cushion and hemodynamic flow abnormalities, American Journal of Physiology-Heart and Circulatory Physiology, 10.1152/ajpheart.00188.2016, 311:5, (H1150-H1159), Online publication date: 1-Nov-2016. Maeda K, Asai R, Maruyama K, Kurihara Y, Nakanishi T, Kurihara H and Miyagawa-Tomita S (2016) Postotic and preotic cranial neural crest cells differently contribute to thyroid development, Developmental Biology, 10.1016/j.ydbio.2015.10.026, 409:1, (72-83), Online publication date: 1-Jan-2016. Guadix J and Pérez-Pomares J (2016) Molecular Pathways and Animal Models of Coronary Artery Anomalies Congenital Heart Diseases: The Broken Heart, 10.1007/978-3-7091-1883-2_45, (541-552), . Slesnick T, Sachdeva R, Kreeger J and Border W (2016) Truncus Arteriosus and Aortopulmonary Window Echocardiography in Pediatric and Congenital Heart Disease, 10.1002/9781118742440.ch23, (433-445) Meindl C, Achatz B, Huber D, Baessler A, Hubauer U, Meisinger C, Hengstenberg C, Erdmann J, Buchner S, Maier L, Schunkert H, Debl K and Fischer M (2016) Coronary Artery Ectasia Are Frequently Observed in Patients With Bicuspid Aortic Valves With and Without Dilatation of the Ascending Aorta, Circulation: Cardiovascular Interventions, 9:10, Online publication date: 1-Oct-2016. Tapia G, Zhu X, Xu J, Liang P, Su G, Liu H, Liu Y, Shu L, Liu S and Huang C (2015) Incidence of Branching Patterns Variations of the Arch in Aortic Dissection in Chinese Patients, Medicine, 10.1097/MD.0000000000000795, 94:17, (e795), Online publication date: 1-May-2015. Cesario J, Malt A and Jeong J (2015) Developmental Genetics of the Pharyngeal Arch System, Colloquium Series on Developmental Biology, 10.4199/C00127ED1V01Y201503DEB006, 2:1, (1-108), Online publication date: 14-May-2015. UDDIN M, KIMURA W, ISHIKURA T, KOSEKI H, YOSHIDA N, ISLAM M, AMIN M, NAKAMURA K, WU Y, SATO E, AOTO K and MIURA N (2015) Foxc2 in pharyngeal arch mesenchyme is important for aortic arch artery remodelling and ventricular septum formation , Biomedical Research, 10.2220/biomedres.36.235, 36:4, (235-245), . van Gelder M, van Rooij I, de Jong-van den Berg L and Roeleveld N (2014) Teratogenic Mechanisms Associated with Prenatal Medication Exposure, Therapies, 10.2515/therapie/2014003, 69:1, (13-24), Online publication date: 1-Jan-2014. Cock D, Meuris B, Benett J and Desmet W (2013) Spontaneous bilateral carotid artery dissection in a patient with bovine aortic arch, Vascular, 10.1177/1708538113489283, 22:4, (293-296), Online publication date: 1-Aug-2014. Karunamuni G, Ma P, Gu S, Rollins A, Jenkins M and Watanabe M (2014) Connecting teratogen-induced congenital heart defects to neural crest cells and their effect on cardiac function, Birth Defects Research Part C: Embryo Today: Reviews, 10.1002/bdrc.21082, 102:3, (227-250), Online publication date: 1-Sep-2014. Krishnamurthy V, Evans A, Wansapura J, Osinska H, Maddy K, Biechler S, Narmoneva D, Goodwin R and Hinton R (2014) Asymmetric Cell–Matrix and Biomechanical Abnormalities in Elastin Insufficiency Induced Aortopathy, Annals of Biomedical Engineering, 10.1007/s10439-014-1072-y, 42:10, (2014-2028), Online publication date: 1-Oct-2014. ten Donkelaar H, Vermeij-Keers C and Mathijssen I (2014) The Neural Crest and Craniofacial Malformations Clinical Neuroembryology, 10.1007/978-3-642-54687-7_5, (219-269), . Yutzey K, Demer L, Body S, Huggins G, Towler D, Giachelli C, Hofmann-Bowman M, Mortlock D, Rogers M, Sadeghi M and Aikawa E (2014) Calcific Aortic Valve Disease, Arteriosclerosis, Thrombosis, and Vascular Biology, 34:11, (2387-2393), Online publication date: 1-Nov-2014. Xia Z, Tong X, Liang F, Zhang Y, Kuok C, Zhang Y, Liu X, Zhu Z, Lin S and Zhang B (2013) Eif3ba regulates cranial neural crest development by modulating p53 in zebrafish, Developmental Biology, 10.1016/j.ydbio.2013.06.009, 381:1, (83-96), Online publication date: 1-Sep-2013. Lee M, Sung J, Cho S, Choi S, Cho S, Oh J, Park S and Kim D (2012) Aortic dilatation and calcification in asymptomatic patients with bicuspid aortic valve: analysis in a Korean health screening population, The International Journal of Cardiovascular Imaging, 10.1007/s10554-012-0116-3, 29:3, (553-560), Online publication date: 1-Mar-2013. Wanamaker K, Amadi C, Mueller J and Moraca R (2013) Incidence of Aortic Arch Anomalies in Patients with Thoracic Aortic Dissections, Journal of Cardiac Surgery, 10.1111/jocs.12072, 28:2, (151-154), Online publication date: 1-Mar-2013. Garg V (2012) Growth of the Normal Human Heart Handbook of Growth and Growth Monitoring in Health and Disease, 10.1007/978-1-4419-1795-9_78, (1305-1316), . Szili-Torok T, van Malderen S and de Groot N (2012) 'Born' with a 'dead'-end-tract resulting in arrhythmias in the aorto-mitral continuity: coincidence, causation, and 'commensuration', Europace, 10.1093/europace/eur433, 14:3, (308-309), Online publication date: 1-Mar-2012. Garg V (2012) Molecular Basis of Cardiac Development and Congenital Heart Disease Translational Cardiology, 10.1007/978-1-61779-891-7_10, (317-339), . Yamagishi H (2012) Cardiac Neural Crest and Congenital Heart Defects, Pediatric Cardiology and Cardiac Surgery, 10.9794/jspccs.28.110, 28:2, (110-116), . Malone C, Urbania T, Crook S and Hope M (2012) Bovine aortic arch: A novel association with thoracic aortic dilation, Clinical Radiology, 10.1016/j.crad.2011.04.004, 67:1, (28-31), Online publication date: 1-Jan-2012. Liu D, Gilbert M, Kempf D and Didier P (2011) Double-outlet right ventricle and double septal defects in a Rhesus macaque ( Macaca mulatta ) , Journal of Veterinary Diagnostic Investigation, 10.1177/1040638711425951, 24:1, (188-191), Online publication date: 1-Jan-2012. Gittenberger-de Groot A, Jongbloed M, Poelmann R and Bartelings M (2012) Structural heart disease Fetal Therapy, 10.1017/CBO9780511997778.012, (100-112) Nathan D, Xu C, Gorman J, Fairman R, Bavaria J, Gorman R, Chandran K and Jackson B (2011) Pathogenesis of Acute Aortic Dissection: A Finite Element Stress Analysis, The Annals of Thoracic Surgery, 10.1016/j.athoracsur.2010.10.042, 91:2, (458-463), Online publication date: 1-Feb-2011. Helbok R, Beer R, Chemelli A, Sohm F, Broessner G, Lackner P, Sojer M, Pfausler B, Thomé C and Schmutzhard E (2011) Multimodal Neuromonitoring in a Patient with Aneurysmal Subarachnoid Hemorrhage Associated with Aortic Coarctation, Neurocritical Care, 10.1007/s12028-011-9503-1, 14:3, (433-437), Online publication date: 1-Jun-2011. Kuo B and Erickson C (2011) Vagal neural crest cell migratory behavior: A transition between the cranial and trunk crest, Developmental Dynamics, 10.1002/dvdy.22715, 240:9, (2084-2100), Online publication date: 1-Sep-2011. Luis A, Bret M, Cuesta E, Aras R, Xiaomei L, Encinas J, Martinez L and Tovar J (2010) Microscopic magnetic resonance imaging of the thoracic venous system in rats with congenital diaphragmatic hernia, Pediatric Surgery International, 10.1007/s00383-010-2789-9, 27:2, (175-180), Online publication date: 1-Feb-2011. Tan T, Gordon C, Amor D and Farlie P (2010) Developmental perspectives on copy number abnormalities of the 22q11.2 region, Clinical Genetics, 10.1111/j.1399-0004.2010.01456.x, 78:3, (201-218) Chapman-Fredricks J, Birusingh R, Ricci M and Rodriguez M (2010) INTRACAVAL LIVER WITH CARDIAC EXTENSION. A NEW DEVELOPMENTAL ANOMALY?, Fetal and Pediatric Pathology, 10.3109/15513815.2010.505622, 29:6, (401-406), Online publication date: 1-Nov-2010. Grossmann K, Rosário M, Birchmeier C and Birchmeier W (2010) The Tyrosine Phosphatase Shp2 in Development and Cancer , 10.1016/S0065-230X(10)06002-1, (53-89), . Kouwenberg M, Draaisma J, Kuijpers-Jagtman A and Bartzela T (2012) Bijkomende aangeboren aandoeningen bij een complete dubbelzijdige cheilognathopalatoschisis, Tijdschrift voor Kindergeneeskunde, 10.1007/s12456-010-0004-5, 78:1, (15-20), Online publication date: 1-Feb-2010. Reddy P, Rajagopal G, Harinarayan C, Vanaja V, Rajasekhar D, Suresh V and Sachan A (2010) High Prevalence of Associated Birth Defects in Congenital Hypothyroidism, International Journal of Pediatric Endocrinology, 10.1186/1687-9856-2010-940980, 2010:1, (940980), . Bechtel J, Misfeld M, Schmidtke C and Sievers H (2010) The bicuspid aortic valve Aortic Root Surgery, 10.1007/978-3-7985-1869-8_9, (89-101), . Lee M, Chen M, Yang A and Chiu I (2010) Mirror-image type D interrupted aortic arch: A novel cardiac phenotype providing some perspective in the del22q11.2 syndrome, International Journal of Cardiology, 10.1016/j.ijcard.2008.11.153, 141:3, (e47-e50), Online publication date: 1-Jun-2010. Hutson M and Kirby M (2010) Role of Cardiac Neural Crest in the Development of the Caudal Pharyngeal Arches, the Cardiac Outflow and Disease Heart Development and Regeneration, 10.1016/B978-0-12-381332-9.00021-9, (441-462), . van Gelder M, van Rooij I, Miller R, Zielhuis G, de Jong-van den Berg L and Roeleveld N (2010) Teratogenic mechanisms of medical drugs, Human Reproduction Update, 10.1093/humupd/dmp052, 16:4, (378-394), Online publication date: 1-Jul-2010. Soh C, Lim J, Boyd R and Chidgey A (2009) Epithelial Stem Cells and the Development of the Thymus, Parathyroid, and Skin Regulatory Networks in Stem Cells, 10.1007/978-1-60327-227-8_33, (405-437), . Digilio M, McDonald-McGinn D, Heike C, Catania C, Dallapiccola B, Marino B and Zackai E (2009) Three patients with oculo-auriculo-vertebral spectrum and microdeletion 22q11.2, American Journal of Medical Genetics Part A, 10.1002/ajmg.a.33034, 149A:12, (2860-2864), Online publication date: 1-Dec-2009. Radu N, Gervais M, Allaire E, Loisance D and Kirsch M (2009) Physiopathologie des anévrismes idiopathiques de l'aorte thoracique ascendante, La Presse Médicale, 10.1016/j.lpm.2008.09.023, 38:7-8, (1076-1088), Online publication date: 1-Jul-2009. Sloot W, Bowden H and Yih T (2009) In vitro and in vivo reproduction toxicology of 12 monoaminergic reuptake inhibitors: Possible mechanisms of infrequent cardiovascular anomalies, Reproductive Toxicology, 10.1016/j.reprotox.2009.04.005, 28:2, (270-282), Online publication date: 1-Sep-2009. Moon A (2008) Chapter 4 Mouse Models of Congenital Cardiovascular Disease Mouse Models of Developmental Genetic Disease, 10.1016/S0070-2153(08)00604-2, (171-248), . Nie X, Deng C, Wang Q and Jiao K (2008) Disruption of Smad4 in neural crest cells leads to mid-gestation death with pharyngeal arch, craniofacial and cardiac defects, Developmental Biology, 10.1016/j.ydbio.2008.02.006, 316:2, (417-430), Online publication date: 1-Apr-2008. Hakim Z, DiMichele L, Doherty J, Homeister J, Beggs H, Reichardt L, Schwartz R, Brackhan J, Smithies O, Mack C and Taylor J (2007) Conditional Deletion of Focal Adhesion Kinase Leads to Defects in Ventricular Septation and Outflow Tract Alignment, Molecular and Cellular Biology, 10.1128/MCB.00068-07, 27:15, (5352-5364), Online publication date: 1-Aug-2007. Zhu H, Wlodarczyk B, Scott M, Yu W, Merriweather M, Gelineau-van Waes J, Schwartz R and Finnell R (2007) Cardiovascular abnormalities inFolr1 knockout mice and folate rescue, Birth Defects Research Part A: Clinical and Molecular Teratology, 10.1002/bdra.20347, 79:4, (257-268), Online publication date: 1-Apr-2007. Sanlaville D and Verloes A (2007) CHARGE syndrome: an update, European Journal of Human Genetics, 10.1038/sj.ejhg.5201778, 15:4, (389-399), Online publication date: 1-Apr-2007. Schleiffarth J, Person A, Martinsen B, Sukovich D, Neumann A, Baker C, Lohr J, Cornfield D, Ekker S and Petryk A (2007) Wnt5a Is Required for Cardiac Outflow Tract Septation in Mice, Pediatric Research, 10.1203/pdr.0b013e3180323810, 61:4, (386-391), Online publication date: 1-Apr-2007. Sievers H (2007) In vivo tissue engineering an autologous semilunar biovalve: Can we get what we want?, The Journal of Thoracic and Cardiovascular Surgery, 10.1016/j.jtcvs.2007.03.028, 134:1, (20-22.e1), Online publication date: 1-Jul-2007. Wintner S, Hafner E, Stonek F, Stuempflen I, Metzenbauer M and Philipp K (2007) Association of congenital cardiac defects and the C677T methylenetetrahydrofolate reductase polymorphism, Prenatal Diagnosis, 10.1002/pd.1761, 27:8, (704-708), Online publication date: 1-Aug-2007. Longo M, Zanoncelli S, Torre P, Riflettuto M, Cocco F, Pesenti M, Giusti A, Colombo P, Brughera M, Mazué G, Navaratman V, Gomes M and Olliaro P (2006) In vivo and in vitro investigations of the effects of the antimalarial drug dihydroartemisinin (DHA) on rat embryos, Reproductive Toxicology, 10.1016/j.reprotox.2006.08.001, 22:4, (797-810), Online publication date: 1-Nov-2006. Cipollone D, Amati F, Carsetti R, Placidi S, Biancolella M, D'Amati G, Novelli G, Siracusa G and Marino B (2006) A multiple retinoic acid antagonist induces conotruncal anomalies, including transposition of the great arteries, in mice, Cardiovascular Pathology, 10.1016/j.carpath.2006.04.004, 15:4, (194-202), Online publication date: 1-Jul-2006. Arnold J, Werling U, Braunstein E, Liao J, Nowotschin S, Edelmann W, Hebert J and Morrow B (2006) Inactivation of Tbx1 in the pharyngeal endoderm results in 22q11DS malformations , Development, 10.1242/dev.02264, 133:5, (977-987), Online publication date: 1-Mar-2006. Crane J and Trainor P (2006) Neural Crest Stem and Progenitor Cells, Annual Review of Cell and Developmental Biology, 10.1146/annurev.cellbio.22.010305.103814, 22:1, (267-286), Online publication date: 1-Nov-2006. Lee M, Chen H, Chen M, Tsao L, Wang B, Lee M and Chiu I (2006) Persistent Fifth Aortic Arch Associated with 22q11.2 Deletion Syndrome, Journal of the Formosan Medical Association, 10.1016/S0929-6646(09)60119-4, 105:4, (284-289), . Gonzalez-Reyes S, Fernandez-Dumont V, Calonge W, Martinez L and Tovar J (2005) Expression of Connexin 43 in the hearts of rat embryos exposed to nitrofen and effects of vitamin A on it, Pediatric Surgery International, 10.1007/s00383-005-1583-6, 22:1, (61-65), Online publication date: 1-Jan-2006. Holländer G, Gill J, Zuklys S, Iwanami N, Liu C and Takahama Y (2006) Cellular and molecular events during early thymus development, Immunological Reviews, 10.1111/j.0105-2896.2006.00357.x, 209:1, (28-46), Online publication date: 1-Feb-2006. Bennett G, Moser K, Chaudoin T and Rosenquist T (2006) The expression of the NR1-subunit of the NMDA receptor during mouse and early chicken development, Reproductive Toxicology, 10.1016/j.reprotox.2006.03.010, 22:3, (536-541), Online publication date: 1-Oct-2006. Sato M, Tsai H and Yost H (2006) Semaphorin3D regulates invasion of cardiac neural crest cells into the primary heart field, Developmental Biology, 10.1016/j.ydbio.2006.05.033, 298:1, (12-21), Online publication date: 1-Oct-2006. Zhang N, Mustin D, Reardon W, Almeida A, Mozdziak P, Mrug M, Eisenberg L and Sedmera D (2006) Blood-Borne Stem Cells Differentiate into Vascular and Cardiac Lineages During Normal Development, Stem Cells and Development, 10.1089/scd.2006.15.17, 15:1, (17-28), Online publication date: 1-Feb-2006. Katzman P, Smoot L and Cox G (2006) Cardiac Registry Screening for DiGeorge Critical Region Deletion Using Loss of Heterozygosity Analysis, Pediatric and Developmental Pathology, 10.2350/06-02-0041.1, 9:4, (266-279), Online publication date: 1-Jul-2006. ten Donkelaar H and Vermeij-Keers C (2006) The Neural Crest and Craniofacial Malformations Clinical Neuroembryology, 10.1007/3-540-34659-7_5, (191-228), . Sato M and Yost H (2007) Neural Crest Cells Contribute to Heart Formation and Cardiomyogenesis in Zebrafish Cardiovascular Development and Congenital Malformations, 10.1002/9780470988664.ch38, (150-152) Verloes A (2005) Updated diagnostic criteria for CHARGE syndrome: A proposal, American Journal of Medical Genetics Part A, 10.1002/ajmg.a.30559, 133A:3, (306-308), Online publication date: 15-Mar-2005. Mohamed S, Techel D, Li L, Erasmi A and Sievers H (2005) Molekulargenetische Studien bikuspider AortenklappenMolecular genetic studies on bicuspid aortic valve, Zeitschrift für Herz-,Thorax- und Gefäßchirurgie, 10.1007/s00398-005-0510-4, 19:5, (227-233), Online publication date: 1-Oct-2005. González-Reyes S, Martínez L and Tovar J (2005) Effects of prenatal vitamins A, E, and C on the hypoplastic hearts of fetal rats with diaphragmatic hernia, Journal of Pediatric Surgery, 10.1016/j.jpedsurg.2005.05.009, 40:8, (1269-1274), Online publication date: 1-Aug-2005. Byrd N and Meyers E (2005) Loss of Gbx2 results in neural crest cell patterning and pharyngeal arch artery defects in the mouse embryo, Developmental Biology, 10.1016/j.ydbio.2005.05.023, 284:1, (233-245), Online publication date: 1-Aug-2005. Mohamed S, Hanke T, Schlueter C, Bullerdiek J and Sievers H (2005) Ubiquitin fusion degradation 1–like gene dysregulation in bicuspid aortic valve, The Journal of Thoracic and Cardiovascular Surgery, 10.1016/j.jtcvs.2005.08.017, 130:6, (1531-1536), Online publication date: 1-Dec-2005. Managoli S, Chaturvedi P, Vilhekar K and Gagane N (2004) Unilateral pulmonary agenesis and renal anomalies associated within situ neuroblastoma of the adrenal gland, The Indian Journal of Pediatrics, 10.1007/BF02724300, 71:6, (545-547), Online publication date: 1-Jun-2004. Chan W, Cheung C, Yung K and Copp A (2004) Cardiac neural crest of the mouse embryo: axial level of origin,migratory pathway and cell autonomy of the splotch ( Sp2H ) mutant effect , Development, 10.1242/dev.01197, 131:14, (3367-3379), Online publication date: 15-Jul-2004. Rauch A, Hofbeck M, Cesnjevar R, Koch A, Rauch R, Buheitel G, Singer H and Weyand M (2003) Search for somatic 22q11.2 deletions in patients with conotruncal heart defects, American Journal of Medical Genetics, 10.1002/ajmg.a.20323, 124A:2, (165-169), Online publication date: 15-Jan-2004. Sieber-Blum M (2003) Cardiac neural crest stem cells, The Anatomical Record, 10.1002/ar.a.10132, 276A:1, (34-42), Online publication date: 1-Jan-2004. Bernd P, Miles K, Rozenberg I, Borghjid S and Kirby M (2004) Neurotrophin-3 and TrkC are expressed in the outflow tract of the developing chicken heart, Developmental Dynamics, 10.1002/dvdy.20084, 230:4, (767-772), Online publication date: 1-Aug-2004. von Kodolitsch Y, Ito W, Franzen O, Lund G, Koschyk D and Meinertz T (2004) Coronary artery anomaliesAnomalien der Koronararterien Teil I: Aktuelle Erkenntnisse aus der Embryologie, Zeitschrift für Kardiologie, 10.1007/s00392-004-0152-7, 93:12, (929-937), Online publication date: 1-Dec-2004. Gill J, Malin M, Sutherland J, Gray D, Hollander G and Boyd R (2003) Thymic generation and regeneration, Immunological Reviews, 10.1034/j.1600-065X.2003.00077.x, 195:1, (28-50) Boot M, Gittenberger-De Groot A, Van Iperen L, Hierck B and Poelmann R (2003) Spatiotemporally separated cardiac neural crest subpopulations that target the outflow tract septum and pharyngeal arch arteries, The Anatomical Record, 10.1002/ar.a.10099, 275A:1, (1009-1018), Online publication date: 1-Nov-2003. Hibbert B, Olsen S and O'Brien E (2003) Involvement of Progenitor Cells in Vascular Repair, Trends in Cardiovascular Medicine, 10.1016/j.tcm.2003.09.002, 13:8, (322-326), Online publication date: 1-Nov-2003. Ali M, Farooqui F and Sohal G (2003) Ventrally emigrating neural tube cells contribute to the normal development of heart and great vessels, Vascular Pharmacology, 10.1016/S1537-1891(03)00003-X, 40:2, (133-140), Online publication date: 1-Feb-2003. Tallquist M and Soriano P (2003) Cell autonomous requirement for PDGFRα in populations of cranial and cardiac neural crest cells, Development, 10.1242/dev.00241, 130:3, (507-518), Online publication date: 1-Feb-2003. Azhar M, Schultz J, Grupp I, Dorn G, Meneton P, Molin D, Gittenberger-de Groot A and Doetschman T (2003) Transforming growth factor beta in cardiovascular development and function, Cytokine & Growth Factor Reviews, 10.1016/S1359-6101(03)00044-3, 14:5, (391-407), Online publication date: 1-Oct-2003. Hoch R and Soriano P (2003) Roles of PDGF in animal development, Development, 10.1242/dev.00721, 130:20, (4769-4784), Online publication date: 15-Oct-2003. Sato M and Yost H (2003) Cardiac neural crest contributes to cardiomyogenesis in zebrafish, Developmental Biology, 10.1016/S0012-1606(03)00037-X, 257:1, (127-139), Online publication date: 1-May-2003. Macatee T, Hammond B, Arenkiel B, Francis L, Frank D and Moon A (2003) Ablation of specific expression domains reveals discrete functions of ectoderm- and endoderm-derived FGF8 during cardiovascular and pharyngeal development, Development, 10.1242/dev.00850, 130:25, (6361-6374), Online publication date: 22-Dec-2003. Shashi V, Berry M and Hines M (2003) Vasomotor instability in neonates with chromosome 22q11 deletion syndrome, American Journal of Medical Genetics, 10.1002/ajmg.a.20219, 121A:3, (231-234), Online publication date: 1-Sep-2003. Digilio M, Angioni A, Giannotti A, Dallapiccola B and Marino B (2003) Truncus arteriosus and duplication 8q, American Journal of Medical Genetics, 10.1002/ajmg.a.20054, 121A:1, (79-81), Online publication date: 15-Aug-2003. Yun K (2002) Ascending aortic aneurysm and aortic root disease, Coronary Artery Disease, 10.1097/00019501-200204000-00002, 13:2, (79-84), Online publication date: 1-Apr-2002. Mercado R, López S, Cantú C, Sanchez A, Revuelta R, Gómez-Llata S, Bouffard J and Pineda C Intracranial aneurysms associated with unsuspected aortic coarctation, Journal of Neurosurgery, 10.3171/jns.2002.97.5.1221, 97:5, (1221-1225) Kochilas L, Merscher-Gomez S, Lu M, Potluri V, Liao J, Kucherlapati R, Morrow B and Epstein J (2002) The Role of Neural Crest during Cardiac Development in a Mouse Model of DiGeorge Syndrome, Developmental Biology, 10.1006/dbio.2002.0819, 251:1, (157-166), Online publication date: 1-Nov-2002. Frank D, Fotheringham L, Brewer J, Muglia L, Tristani-Firouzi M, Capecchi M and Moon A (2002) An Fgf8 mouse mutant phenocopies human 22q11 deletion syndrome , Development, 10.1242/dev.129.19.4591, 129:19, (4591-4603), Online publication date: 1-Oct-2002. Villanueva M, Aiyer A, Muller S, Pletcher M, Liu X, Emanuel B, Srivastava D and Reeves R (2002) Genetic and Comparative Mapping of Genes Dysregulated in Mouse Hearts Lacking the Hand2 Transcription Factor Gene, Genomics, 10.1006/geno.2002.7009, 80:6, (593-600), Online publication date: 1-Dec-2002. Gill J, Malin M, Holländer G and Boyd R (2002) Generation of a complete thymic microenvironment by MTS24+ thymic epithelial cells, Nature Immunology, 10.1038/ni812, 3:7, (635-642), Online publication date: 1-Jul-2002. Tsujita-Kuroda Y, Nakatani S, Hirooka K, Andoh M, Nakasone I, Yasuda H, Kanzaki H, Kawamura A, Hanatani A, Yasumura Y, Yamagishi M and Miyatake K (2002) Bicuspid aortic valve stenosis complicated by descending aortic dissection mimicking coarctation of the aorta, Journal of the American Society of Echocardiography, 10.1067/mje.2002.121440, 15:9, (994-996), Online publication date: 1-Sep-2002. Marino B, Digilio M and Toscano A (2002) Common arterial trunk, DiGeorge syndrome and microdeletion 22q11, Progress in Pediatric Cardiology, 10.1016/S1058-9813(02)00004-8, 15:1, (9-17), Online publication date: 1-Jun-2002. Shah M, Morava E, Gill W and Marble M (2002) Transposition of the Great Arteries and Hypocalcemia in a Patient With Fetal Hydantoin Syndrome, Journal of Perinatology, 10.1038/sj.jp.7210596, 22:1, (89-90), Online publication date: 1-Jan-2002. Ursem N, Clark E, Pagotto L and Wladimiroff J (2002) Fetal heart rate and umbilical artery velocity variability in fetuses with congenital cardiac defects: a preliminary study, Ultrasound in Obstetrics and Gynecology, 10.1046/j.1469-0705.2001.00435.x, 18:2, (135-140), Online publication date: 1-Aug-2001. Keller B (2001) Function and Biomechanics of Developing Cardiovascular Systems Formation of the Heart and Its Regulation, 10.1007/978-1-4612-0207-3_13, (251-271), . Garg V, Yamagishi C, Hu T, Kathiriya I, Yamagishi H and Srivastava D (2001) Tbx1, a DiGeorge Syndrome Candidate Gene, Is Regulated by Sonic Hedgehog during Pharyngeal Arch Development, Developmental Biology, 10.1006/dbio.2001.0283, 235:1, (62-73), Online publication date: 1-Jul-2001. Parmacek M (2001) Transcriptional programs regulating vascular smooth muscle cell development and differentiation , 10.1016/S0070-2153(01)51002-9, (69-89), . Rosenquist T and Finnell R (2007) Genes, folate and homocysteine in embryonic development, Proceedings of the Nutrition Society, 10.1017/S0029665101000088, 60:1, (53-61), Online publication date: 1-Feb-2001. Cox J and Briner J (2001) The Cardiovascular System Fetal and Neonatal Pathology, 10.1007/978-1-4471-3682-8_18, (471-523), . Merscher S, Funke B, Epstein J, Heyer J, Puech A, Lu M, Xavier R, Demay M, Russell R, Factor S, Tokooya K, Jore B, Lopez M, Pandita R, Lia M, Carrion D, Xu H, Schorle H, Kobler J, Scambler P, Wynshaw-Boris A, Skoultchi A, Morrow B and Kucherlapati