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Acute infectious urticaria

1946; Elsevier BV; Volume: 28; Issue: 5 Linguagem: Inglês

10.1016/s0022-3476(46)80225-7

1097-6833

Lee Bivings,

Urticaria and Related Conditions

Summary 1.Twenty-two cases of acute infectious urticaria were observed between February, 1943, and May, 1944. 2.Seventeen cases associated with upper respiratory infections were seenin the winter months, October to March, inclusive. 3.Thirteen patients were males and nine were females. 4.Fourteen were under 3 years and eight from 3 to 10 years of age. 5.History of allergy was negative in eighteen, positive in three, and unknown in one. 6.Three were acutely ill; nineteen were moderately or mildly ill. 7.Nineteen urticaries were associated with acute throat infections, two with acute otitis media, and one with pyelitis. 8.The three most acutely ill had white blood cell counts of 20,000 or above, with high neutrophile counts. One had a high eosinophilia. Blood cultures were negative in five. Throat cultures showed no common organism in six instances. 9.Two of the children had second attacks, three weeks and three monthslater, respectively. 10.A sulfonamide was considered a possible etiological factor in one, but the rash preceded the drug in the remaining twenty-one in which it was used to clear the focus of infection with no effect on the rash. Local treatment of the rash with calamine lotion seemed much more effective than ephedrine, adrenalin, histaminase or other systemic treatment. Summary 1.Twenty-two cases of acute infectious urticaria were observed between February, 1943, and May, 1944. 2.Seventeen cases associated with upper respiratory infections were seenin the winter months, October to March, inclusive. 3.Thirteen patients were males and nine were females. 4.Fourteen were under 3 years and eight from 3 to 10 years of age. 5.History of allergy was negative in eighteen, positive in three, and unknown in one. 6.Three were acutely ill; nineteen were moderately or mildly ill. 7.Nineteen urticaries were associated with acute throat infections, two with acute otitis media, and one with pyelitis. 8.The three most acutely ill had white blood cell counts of 20,000 or above, with high neutrophile counts. One had a high eosinophilia. Blood cultures were negative in five. Throat cultures showed no common organism in six instances. 9.Two of the children had second attacks, three weeks and three monthslater, respectively. 10.A sulfonamide was considered a possible etiological factor in one, but the rash preceded the drug in the remaining twenty-one in which it was used to clear the focus of infection with no effect on the rash. Local treatment of the rash with calamine lotion seemed much more effective than ephedrine, adrenalin, histaminase or other systemic treatment.