Mamanine and pohakuline, two unprecedented quinolizidine alkaloids from sophora chrysophylla
1976; Elsevier BV; Volume: 32; Issue: 8 Linguagem: Inglês
10.1016/0040-4020(76)85049-1
ISSN1464-5416
AutoresMavis M. Kadooka, Mildred Y. Chang, Hiroshi Fukami, Paul J. Scheuer, Jon Clardy, Barbara A. Solheim, James P. Springer,
Tópico(s)Botanical Research and Chemistry
ResumoFrom the bark of the endemic Hawaiian tree Sophora chrysophylla Seem. we have isolated two unprecedented quainolizidine alkaloids, mamanine (4) and pohakuline (5). Both bases are 1-hydroxymethylenequinolizidines which are linked at C-3 to α-pyridone or α-piperidone moieties. The alkaloids may be intermediates in a heretofore unknown biogenetic pathway of Sophora alkaloids.
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