Diffusion tensor imaging in refractory epilepsy
2002; Elsevier BV; Volume: 359; Issue: 9319 Linguagem: Inglês
10.1016/s0140-6736(02)08615-4
ISSN1474-547X
AutoresFergus Rugg‐Gunn, Sofia Eriksson, Mark R. Symms, Gareth J. Barker, Maria Thom, William Harkness, John S. Duncan,
Tópico(s)Epilepsy research and treatment
ResumoSummary Diffusion tensor imaging is an imaging method that is sensitive to the molecular movement of water, which indicates cellular integrity and pathology. A patient with refractory epilepsy and normal conventional MRI was examined with diffusion tensor imaging. An area of abnormal diffusion in the right frontal lobe was identified and surgically resected. The patient had a good clinical outcome. Histopathological examination of the resected tissue showed gliosis. Our findings may affect the investigation of similar patients, and provide histopathological confirmation of diffusion abnormalities.
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