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Performance of the Molecular Alere i Influenza A&B Test Compared to That of the Xpert Flu A/B Assay

2014; American Society for Microbiology; Volume: 53; Issue: 2 Linguagem: Inglês

10.1128/jcm.02783-14

1098-660X

Kimberle C. Chapin, Estefany Flores-Cortez,

SARS-CoV-2 detection and testing

Data on the performance of rapid molecular point-of-care use platforms for diagnosis of influenza are lacking. We validated nasopharyngeal (NP) flocked specimens in universal transport medium (UTM) and evaluated the clinical sensitivity and specificity of the Alere i influenza A&B test compared to those of the Xpert flu A/B assay. The Alere i influenza A&B test had an overall sensitivity and specificity of 93.8% and 62.5% for influenza A, respectively, and of 91.8% and 53.6% for influenza B, respectively. The poor specificity was due to influenza virus samples determined positive for both type A and B.