Brain stem reflexes in patients with Wallenberg's syndrome: Correlation with clinical and magnetic resonance imaging (MRI) findings
1996; Wiley; Volume: 19; Issue: 9 Linguagem: Inglês
10.1002/(sici)1097-4598(199609)19
ISSN1097-4598
AutoresJosep Valls-Sol�, Nicol�s Vila, Vı́ctor Obach, Ramiro Álvarez, Luis Ernesto Gonz�lez, Ángel Chamorro,
Tópico(s)Ophthalmology and Visual Health Research
ResumoMuscle & NerveVolume 19, Issue 9 p. 1093-1099 Main Article Brain stem reflexes in patients with Wallenberg's syndrome: Correlation with clinical and magnetic resonance imaging (MRI) findings Josep Valls-Solé MD, Corresponding Author Josep Valls-Solé MD Unitat d'EMG, Servei de Neurología, Hospital Clinic, Departamento de Medecina, Universidad de Barcelona, Barcelona, SpainUnitat d'EMG, Servei de Neurologia, Hospital Clinic, Villarroel 170, Barcelona 08036, SpainSearch for more papers by this authorNicolás Vila MD, Nicolás Vila MD Unitat d'EMG, Servei de Neurología, Hospital Clinic, Departamento de Medecina, Universidad de Barcelona, Barcelona, SpainSearch for more papers by this authorVictor Obach MD, Victor Obach MD Unitat d'EMG, Servei de Neurología, Hospital Clinic, Departamento de Medecina, Universidad de Barcelona, Barcelona, SpainSearch for more papers by this authorRamiro Alvarez MD, Ramiro Alvarez MD Unitat d'EMG, Servei de Neurología, Hospital Clinic, Departamento de Medecina, Universidad de Barcelona, Barcelona, SpainSearch for more papers by this authorLuis Ernesto González MD, Luis Ernesto González MD Unitat d'EMG, Servei de Neurología, Hospital Clinic, Departamento de Medecina, Universidad de Barcelona, Barcelona, SpainSearch for more papers by this authorAngel Chamorro MD, Angel Chamorro MD Unitat d'EMG, Servei de Neurología, Hospital Clinic, Departamento de Medecina, Universidad de Barcelona, Barcelona, SpainSearch for more papers by this author Josep Valls-Solé MD, Corresponding Author Josep Valls-Solé MD Unitat d'EMG, Servei de Neurología, Hospital Clinic, Departamento de Medecina, Universidad de Barcelona, Barcelona, SpainUnitat d'EMG, Servei de Neurologia, Hospital Clinic, Villarroel 170, Barcelona 08036, SpainSearch for more papers by this authorNicolás Vila MD, Nicolás Vila MD Unitat d'EMG, Servei de Neurología, Hospital Clinic, Departamento de Medecina, Universidad de Barcelona, Barcelona, SpainSearch for more papers by this authorVictor Obach MD, Victor Obach MD Unitat d'EMG, Servei de Neurología, Hospital Clinic, Departamento de Medecina, Universidad de Barcelona, Barcelona, SpainSearch for more papers by this authorRamiro Alvarez MD, Ramiro Alvarez MD Unitat d'EMG, Servei de Neurología, Hospital Clinic, Departamento de Medecina, Universidad de Barcelona, Barcelona, SpainSearch for more papers by this authorLuis Ernesto González MD, Luis Ernesto González MD Unitat d'EMG, Servei de Neurología, Hospital Clinic, Departamento de Medecina, Universidad de Barcelona, Barcelona, SpainSearch for more papers by this authorAngel Chamorro MD, Angel Chamorro MD Unitat d'EMG, Servei de Neurología, Hospital Clinic, Departamento de Medecina, Universidad de Barcelona, Barcelona, SpainSearch for more papers by this author First published: September 1996 https://doi.org/10.1002/(SICI)1097-4598(199609)19:9 3.0.CO;2-VCitations: 48AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Abstract In spite of the general clinical uniformity of Wallenberg's syndrome (WS), individual patients present with a slightly different clinical picture, and detailed studies with magnetic resonance imaging (MRI) show differences in the topography of the brain stem lesion. Neurophysiological characterization of the lesion in WS has been known for a long time, but there are no studies on the possible correlation between lesion topography and neurophysiological deficit. Assuming that afferents from the three branches of the trigeminal nerve reach different parts of the trigeminal nuclei, we examined the possible correlation between the lesion topography assessed by the MRI and the neurophysiological deficit, assessed by studying the brain stem reflexes in patients with WS within 2 weeks after stroke. Neurophysiological abnormalities were always located in the afferent branch of the reflexes examined, but not all patients exhibited abnormalities in all responses. The ophthalmic branch was involved in 92.8% of patients, and the mandibular branch in 57.1% of patients. The patients with MRI lesions located in the lower medulla had normal responses with infraorbital or mental nerve stimulation. The results of this neurophysiological study confirm the heterogeneity of WS. Whether the neurophysiological identification of different subgroups of patients is relevant for clinical outcome needs further studies. © 1996 John Wiley & Sons, Inc. References 1 Chia LG, Shen WC: Wallenberg's lateral medullary syndrome with loss of pain and temperature sensation on the contralateral face: clinical, MRI and electrophysiological studies. 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