Ionic Liquid as Catalyst and Reaction Medium: A Simple and Efficient Procedure for Paal–Knorr Furan Synthesis
2010; Taylor & Francis; Volume: 40; Issue: 3 Linguagem: Inglês
10.1080/00397910902978049
ISSN1532-2432
AutoresGangqiang Wang, Zhi Guan, Rongchang Tang, Yan‐Hong He,
Tópico(s)Oxidative Organic Chemistry Reactions
ResumoThe ionic liquid 1-butyl-3-methyl-imidazolium hydrogen sulfate, [bmim]HSO4, efficiently catalyzes Paal–Knorr furan synthesis without any organic solvent. A wide range of aliphatic and aromatic 1,4-diketones easily undergo condensations to form furan derivatives, providing a general and convenient procedure. The Paal–Knorr reaction of ester-substituted 1,4-diketones is first reported. The ionic liquid can be recovered and reused for subsequent runs without any appreciable loss of efficiency.
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