Induction of temporary sterility in female hamsters by an intraperitoneal Silastic-PVP-PGF2α tube
1975; Elsevier BV; Volume: 9; Issue: 6 Linguagem: Inglês
10.1016/0090-6980(75)90077-5
ISSN1878-416X
AutoresI.F. Lau, S.K. Saksena, M. C. Chang,
Tópico(s)RNA Interference and Gene Delivery
ResumoIn the female hamster, temporary sterility for a period of 10 or 15 days was induced by an intraperitoneal Silastic-PVP-tube containing 3.5 or 1.0 mg of PGF2alpha, respectively. All Silastic-PVP-PGF2alpha tube hearing animals regained fertility and delivered normal litters at various times after the placement of the tube. The release rate of 3-H-PGF2alpha from the Silastic-PVP tube was described and their potential use as a drug delivery system discussed.
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