Intestinal sterols. III. Effects of age, sex and diet
1957; Elsevier BV; Volume: 66; Issue: 1 Linguagem: Inglês
10.1016/0003-9861(57)90553-2
ISSN1096-0384
Autores Tópico(s)Fatty Acid Research and Health
Resumo1. Male rats excreted more sterol than females; castrates excreted less of all sterols except coprostanol. The ratio of Δ7-cholestenol to cholesterol excreted increased markedly with age. 2. Penicillin and sulfasuxidine depressed the excretion of coprostanol with corresponding increases in cholesterol. Aureomycin, streptomycin, and chloromycetin were without effect. 3. Sterol excretion was essentially the same on a fat-free diet as on 20% of lard. It was increased when cellulose was fed. Cholesterol markedly increased the excretion of coprostanol; squalene and Δ7-cholestenol did not. Δ4-Cholestenone increased the excretion of each of the five sterols measured.
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