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Long-Term Intrathecal Infusion of Outer Surface Protein C From Borrelia burgdorferi Causes Axonal Damage

2011; Oxford University Press; Volume: 70; Issue: 9 Linguagem: Inglês

10.1097/nen.0b013e3182289acd

1554-6578

Simone C. Tauber, Sandra Ribes, Sandra Ebert, Torsten Joseph Heinz, Volker Fingerle, Stephanie Bunkowski, Dominik Kugelstadt, Annette Spreer, Olaf Jahn, Helmut Eiffert, Roland Nau,

Dermatological diseases and infestations

Lyme neuroborreliosis (LNB) is the most frequent tick-borne infectious disease of the central nervous system. In acute LNB and the rare chronic state of infection, patients can experience cognitive deficits such as attention and memory disturbances. During LNB, single compounds of Borrelia burgdorferi sensu lato are released into the subarachnoid space.