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Advances in Near-Infrared Spectroscopy to Study the Brain of the Preterm and Term Neonate

2009; Elsevier BV; Volume: 36; Issue: 4 Linguagem: Inglês

10.1016/j.clp.2009.07.007

1557-9840

Martin Wolf, Gorm Greisen,

Neonatal and fetal brain pathology

This article reviews tissue oximetry and imaging to study the preterm and newborn infant brain by near-infrared spectroscopy. These two technologies are now advanced; nearly 100 reports on their use in newborn infants have been published, and commercial instruments are available. The precision of oximetry, however, is a limitation for its clinical use of assessing cerebral oxygenation. Imaging of brain function needs very well defined protocols for sensory stimulation as well as signal analysis to provide meaningful results.