Produção Nacional
Revisado por pares
Combined Use of Late Phase Dimercapto-Succinic Acid Renal Scintigraphy and Ultrasound as First Line Screening After Urinary Tract Infection in Children
2010; Lippincott Williams & Wilkins; Volume: 185; Issue: 1 Linguagem: Inglês
10.1016/j.juro.2010.09.029
ISSN1527-3792
AutoresIsabel Gomes Quirino, Jose Maria P. Silva, José Silvério Santos Diniz, Eleonora Moreira Lima, Ana Cristina S. Rocha, Ana Cristina Simões e Silva, Eduardo A. Oliveira,
Tópico(s)Urological Disorders and Treatments
ResumoNo AccessJournal of UrologyPediatric Urology1 Jan 2011Combined Use of Late Phase Dimercapto-Succinic Acid Renal Scintigraphy and Ultrasound as First Line Screening After Urinary Tract Infection in Children Isabel G. Quirino, Jose Maria P. Silva, Jose S. Diniz, Eleonora M. Lima, Ana Cristina S. Rocha, Ana Cristina Simões e Silva, and Eduardo A. Oliveira Isabel G. QuirinoIsabel G. Quirino , Jose Maria P. SilvaJose Maria P. Silva , Jose S. DinizJose S. Diniz , Eleonora M. LimaEleonora M. Lima , Ana Cristina S. RochaAna Cristina S. Rocha , Ana Cristina Simões e SilvaAna Cristina Simões e Silva , and Eduardo A. OliveiraEduardo A. Oliveira View All Author Informationhttps://doi.org/10.1016/j.juro.2010.09.029AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: The aim of this study was to evaluate the diagnostic accuracy of dimercapto-succinic acid renal scintigraphy and renal ultrasound in identifying high grade vesicoureteral reflux in children after a first episode of urinary tract infection. Materials and Methods: A total of 533 children following a first urinary tract infection were included in the analysis. Patients were assessed by 3 diagnostic imaging studies, renal ultrasound, dimercapto-succinic acid scan and voiding cystourethrography. The main event of interest was the presence of high grade (III to V) vesicoureteral reflux. The combined and separate diagnostic accuracy of screening methods was assessed by calculation of diagnostic OR, sensitivity, specificity, positive predictive value, negative predictive value and likelihood ratio. Results: A total of 246 patients had reflux, of whom 144 (27%) had high grade (III to V) disease. Sensitivity, negative predictive value and diagnostic OR of ultrasound for high grade reflux were 83.3%, 90.8% and 7.9, respectively. Dimercapto-succinic acid scan had the same sensitivity as ultrasound but a higher negative predictive value (91.7%) and diagnostic OR (10.9). If both tests were analyzed in parallel by using the OR rule, ie a negative diagnosis was established only when both test results were normal, sensitivity increased to 97%, negative predictive value to 97% and diagnostic OR to 25.3. Only 9 children (6.3%) with dilating reflux had an absence of alterations in both tests. 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Google Scholar © 2011 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byWang H and Nelson C (2022) Top-Down versus Bottom-Up Approach in Children Presenting with Urinary Tract Infection: Comparative Effectiveness Analysis Using RIVUR and CUTIE Data. Reply.Journal of Urology, VOL. 207, NO. 4, (940-941), Online publication date: 1-Apr-2022. Volume 185Issue 1January 2011Page: 258-263 Advertisement Copyright & Permissions© 2011 by American Urological Association Education and Research, Inc.Keywordsvesico-ureteral refluxurinary tract infectionsultrasonographytechnetium Tc 99m dimercaptosuccinic aciddiagnostic imagingMetrics Author Information Isabel G. Quirino More articles by this author Jose Maria P. Silva More articles by this author Jose S. Diniz More articles by this author Eleonora M. Lima More articles by this author Ana Cristina S. Rocha More articles by this author Ana Cristina Simões e Silva More articles by this author Eduardo A. Oliveira More articles by this author Expand All Advertisement PDF downloadLoading ...
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