The role of the eosinophil in the pathogenesis of asthma
1987; Wiley; Volume: 42; Issue: 5 Linguagem: Inglês
10.1111/j.1398-9995.1987.tb02218.x
ISSN1398-9995
Autores Tópico(s)Eosinophilic Esophagitis
ResumoAllergyVolume 42, Issue 5 p. 321-335 Free Access The role of the eosinophil in the pathogenesis of asthma A. J. Wardlaw, Corresponding Author A. J. Wardlaw Department of Allergy and Clinical Immunology, Cardiothoracic Institute, Brompton Hospital, London, EnglandA. J. Wardlaw, Dept. of Allergy and Clinical Immunology, Cardiothoracic Institute, Brompton Hospital, Fulham Road, London SW3 6HP, England.Search for more papers by this authorA. B. Kay, A. B. Kay Department of Allergy and Clinical Immunology, Cardiothoracic Institute, Brompton Hospital, London, EnglandSearch for more papers by this author A. J. Wardlaw, Corresponding Author A. J. Wardlaw Department of Allergy and Clinical Immunology, Cardiothoracic Institute, Brompton Hospital, London, EnglandA. J. Wardlaw, Dept. of Allergy and Clinical Immunology, Cardiothoracic Institute, Brompton Hospital, Fulham Road, London SW3 6HP, England.Search for more papers by this authorA. B. Kay, A. B. Kay Department of Allergy and Clinical Immunology, Cardiothoracic Institute, Brompton Hospital, London, EnglandSearch for more papers by this author First published: July 1987 https://doi.org/10.1111/j.1398-9995.1987.tb02218.xCitations: 69AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References 1 Ackerman, S. J., Kephart, G. M., Haberman, T. M., Greipp, P. R., Gleich, G. J.: Localization of eosinophil granule major basic protein in human basophils. J. Exp. Med. 158, 946– 961, 1983. 2 Ackerman, S. J., Weil, G. J. & Gleich, G. J.: Formation of Charcot-Leyden crystals by human basophils. J. Exp. Med. 155, 1597– 1609, 1982. 3 Anwar, A. R. E. & Kay, A. B.: Membrane receptors for IgG and complement (C4, C3b and C3d) on human eosinophils and neutrophils and their relation to eosinophilia. J. Immunol. 119, 976– 982, 1977. 4 Anwar, A. R. E., McKean, J. R., Smithers, S. R. & Kay, A. B.: Human eosinophil- and neutrophil-mediated killing of schistosomula of Schistosoma mansoni in vitro. I. Enhancment of complement-dependent damage by mast cell derived mediators and formyl methionyl peptides. J. Immunol. 124, 1122– 1129, 1980. 5 Archer, C. B., Page, C. P., Morley, J. & MacDonald, D. M.: Accumulation of inflammatory cells in response to intracutaneous platelet activating factor (PAF-acether) in man. Br. J. Dermatol. 112, 285– 290, 1985. 6 Barnes, P. J., Cuss, F. M. & Palmer, J. B.: The effect of airway epithelium on smooth muscle contractility in bovine trachea. Br. J. Pharmacol. 86, 685– 691, 1985. 7 Bascom, R., Pipkorn, U., Gleich, G., Lichtenstein, L. M. & Naclerio, R. M.: Effect of systemic steroids on eosinophils (EOS) and major basic protein (MBP) during nasal antigen challenge. J. Allergy Clin. Immunol. 77, (Suppl), 246(Abstr.), 1986. 8 Basten, A. & Beeson, P. B.: Mechanism of eosinophilia. II. Role of lymphocyte. J. Exp. Med. 131, 1288– 1305, 1970. 9 Beeson, P. B. & Bass, D. A.: In: The eosinophil. Vol. XIV, Major problems in internal medicine, pp. 161– 214. W. B. Saunders, Philadelphia , 1974. 10 Bjornson, B. H., Harvey, J. M. & Rose, L.: Differential effect of hydrocortisone on eosinophil and neutrophil proliferation. J. Clin. Invest. 76, 924– 929, 1985. 11 Bryant, D. H. & Kay, A. B.:Cutaneous eosinophil accumulation in atopic and non-atopic individuals: the effect of an ECF-A tetrapeptide and histamine. Clin. Allergy 7, 211– 217, 1977. 12 Butterworth, A. E., Wassom, D. L., Gleich, G. J., Loegering, D. A. & David, J. R.: Damage to schistosomula of S. mansoni induced directly by eosinophil major basic protein. J. Immunol. 122, 221– 229, 1979. 13 Capron, M. C. & Capron, A.: The IgE receptors of human eosinophils. In A. B. Kay, (ed.): Aller. 14 Capron, M., Capron, A., Dessaint, J-P., et al.: Fc receptors for IgE on human and rat eosinophils. J. Immunol. 126, 2087– 2092, 1981. 15 Capron, A., Dessaint, J-P., Capron, M. & Joseph, M.: IgE receptors on different cell lines and their role in triggering different immunological mechanisms. Proc. XII Congr. Eur. Acad. Allergol. Clin. Immunol. Rome,. 17– 23, 1983. 16 Capron, M., Jouault, T., Prin, L., et al.: Functional study of a monoclonal antibody to IgE Fc receptor (FcR2) of eosinophils, platelets, and macrophages. J. Exp. Med. 164, 72– 89, 1986. 17 Capron, M., Kusnierz, J. P., Prin, L., et al.: Cytophilic LgE on human blood and tissue eosinophils: detection by flow microfluorometry. J. Immunol. 134, 3013– 3018, 1985. 18 Capron, M., Spiegelberg, H. L., Prin, L., et al.: Role of IgE receptors in effector function of human eosinophils. J. Immunol. 132, 462– 468, 1984. 19 Clark, R. A. F., Gallin, J. I. & Kaplan, A. P.: The selective eosinophil chemotactic activity of histamine. J. Exp. Med. 142, 1462– 1476, 1975. 20 Cockcroft, D. W. & Murdock, K. Y.: Protective effect of inhaled albuterol, cromolyn, beclomethasone and placebo on allergen-induced early asthmatic response (EAR), late asthmatic response (LAR), and allergen induced increase in bronchial responsiveness to inhaled histamine.. J. Allergy Clin. Immunol. 77(Suppl), 122(Abstr.), 1986. 21 Colley, D. G.: Lymphokine-related eosinophil responses. Lymphokine Res. 1, 133– 155, 1980. 22 Colley, D. G.: Eosinophil and immune mechanisms. Eosinophil stimulation promoter (ESP): A lymphokine induced by specific antigen or phytohemagglutinin. J. Immunol. 110, 1419– 1423, 1973. 23 Collins, J. V., Wardlaw, A. J., Cromwell, O., & Kay, A. B.: Mast cells and neutrophils in bronchoalveolar lavage from asthmatics. J. Allergy Clin. Immunol. 77, 209(Abstr.), 1986. 24 Cuss, F. M., Dixon, C. M. & Barnes, P. J.: Effects of inhaled platelet activating factor on pulmonary function and bronchial responsiveness in man. Lancet 2, 189– 191, 1986. 25 De Monchy, J. G. R., Kauffman, H. F., Venge, P., et al.: Bronchoalveolar eosinophilia during allergen-induced late asthmatic reactions. Am. Rev. Respir. Dis. 131, 373– 376, 1985. 26 Denjean, A., Arnoux, B., Lockhart, A., Masse, R., & Benveniste, J.: Modification of alveolar cell population after PAF-acether induced bronchoconstriction in baboons. Am. Rev. Respir. Dis. 129, A3 (Abstr.), 1984. 27 Dessein, A. J., Lenzi, H. L., Bina, J. C., et al.: Modulation of eosinophil cytotoxicity by blood mononuclear cells from healthy subjects and patients with chronic schistosomiasis mansoni. Cell.odulation of eosinophil cytotoxicity by blood mononuclear cells from healthy subjects and patients with chronic schistosomiasis mansoni. Cell.ni. Cell.i. Cell.. Cell.ell. Immunol. 85, 100– 113, 1984. 28 Dessein, A., Vadas, M. A., Nicola, N., Metcalf, D. & David, J. R.: Enhancement of human blood eosinophil cytotoxicity by semi-purified eosinophil colony stimulating factors. J. Exp. Med. 156, 90– 103, 1982. 29 Diaz, P., Galleguillos, F. R., Gonzalez, M. C., Pantin, C. F. A. & Kay, A. B.: Bronchoalveolar lavage in asthma: the effect of disodium cromoglycate (cromolyn) on leukocyte counts, immunoglobulins, and complement. J. Allergy Clin. Immunol. 74, 41– 48, 1984. 30 Diaz, P., Gonzalez, C., Galleguillos, F., Ancic, P. & Kay, A. B.: Eosinophils and macrophages in bronchial mucus and bronchoalveolar lavage during allergen induced late-phase asthmatic reactions. J. Allergy Clin. Immunol. 77, 244 (Abstr.), 1986. 31 Dunnill, M. S.: The pathology of asthma. In R. Porter & J. Birch, (eds.): Identification of asthma, CIBA Foundation Study GP No. 8, pp. 35– 46, Churchill Livingstone, Edinburgh , 1971. 32 Durham, S. R. & Kay, A. B.: Eosinophils, bronchial hyperreactivity and late-phase asthmatic reactions. Clin Allergy 15, 411– 418, 1985. 33 Ellis, A. G.: The pathology anatomy of bronchial asthma. Am. J. Med. Sci. 136, 407, 1908. 34 Filley, W. V., Holley, K. E., Kephart, G. M. & Gleich, G. J.: Identification by immunofluorescence of eosinophil granule major basic protein in lung tissue of patients with bronchial asthma. Lancet 2, 11– 16, 1982. 35 Fischer, E., Capron, M., Prin, L., Kusnierz, J. P. & Kazatchkin, M.: Human eosinophils express CR1 and CR3 complement receptors for cleavage fragments of C3. Cell. Immunol, (in press). 36 Fitzharris, P., Moqbel, R., Thorne, K. J. I., et al.:The effects of eosinophil activating factor on IgG-dependent sulphidopetide leukotriene generation by human eosinophils. Clin. Exp. Immunol. 66, 673– 680, 1986. 37 Flint, K. C., Leung, K. B. P., Hudspith, B. N., Brostoff, J., Pearce, F. L. & Johnson, N. McI.: Bronchoalveolar mast cells in extrinsic asthma: a mechanism for the initiation of antigen specific bronchoconstriction Br. Med. J. 291, 923– 926, 1985. 38 Frigas, E., Loegering, D. A., Solley, G. O., Farrow, G. M. & Gleich, G. J.: Elevated levels of the eosinophil granule major basic protein in the sputum of patients with bronchial asthma. Mayolevated levels of the eosinophil granule major basic protein in the sputum of patients with bronchial asthma. Mayoma. Mayoa. Mayo. Mayoayo Clin. Proc. 56, 345– 353, 1981. 39 Fukuda, T., Dunnette, S. L. Reed, C. E., Ackerman, S. J., Peters, M. S. & Gleich, G. J.: Increased numbers of hypodense eosinophils in the blood of patients with bronchial asthma. Am. Rev. Respir. Dis. 132, 981– 985. 40 Gerblich, A. A., Campbell, A. E. & Schuyler, M. R.: Changes in T-lymphocyte subpopulations after antigenic bronchial provocation in asthmatics. N. Engl. J. Med. 310, 1349– 1352, 1984. 41 Giraldo, B., Blumenthal, M. N. & Spink, W.: Aspirin intolerance and asthma. A clinical and immunological study. Am. Intern. Med. 71, 479– 496, 1969. 42 Gleich, G. J., Loegering, D. A., Kueppers, F. Babaj, S. P. & Mann, K. G.: Physicochemical and biological properties of the major basic protein from guinea pig eosinophil granules. J. Exp. Med. 140, 313– 332. 1974. 43 Gleich, G. J., Loegering, D. A., Mann, K. G. & Maldonado, J. E.:Comparative properties of the Charcot-Leyden crystal protein and the major basic protein from human eosinophils. J. Clin. Invest. 57, 633– 640, 1976. 44 Gleich, G. J., Frigas, E., Loegering, D. A., Wassom, D. L. & Steinmuller, D.: Cytotoxic properites of the eosinophil major basic protein. J. Immunol. 123, 2925– 2927, 1979. 45 Gleich, G. J. & Adolphson, C. R.: The eosinophil leukocyte: structure and function. Adv. Immunol. 39, 177– 253, 1986. 46 Godard, P., Chaintreuil, J., Dannon, M., et al.: Functional assessment of alveolar macrophages: comparison of cells from asthmatics and normal subjects. J. Allergy Clin. Immunol. 70, 88– 93, 1982. 47 Goetzl, E. J. & Austen, K. F.: Purification and synthesis of eosinophilotactic tetrapeptides of human lung tissue: Identification as eosinophil chemotactic factor of anaphylaxis. Proc.Natl. Acad. Sci. U.S.A. 72, 4123– 4127, 1975. 48 Goetzl, E. J. & Austen, K. F.: Natural eosinophilotactic peptides: Evidence of heterogeneity and studies of structure and function. In A. A. F. Mahmoud & K. F. Austen, (eds.): The eosinophil health and disease pp. 149– 165, Grune & Stratton, New York , 1980. 49 Gonzalez, C., Diaz, P., Galleguillos, F., Ancic, P. & Kay, A. B.: T helper (TH) and suppressor (TS) cells in bronchoalveolar lavage during antigen-induced late-phase asthmatic reactions. J. Allergy Clin. Immunol. 77, 244 (Abstr.), 1986. 50 Gordon, A. S.: Some aspects of hormonal influence upon the leucocytes. Ann. N. Y. Acad. Sci. 59, 907– 927, 1955. 51 Griffith, T. M., Edwards, D. H. & Lewis, M. T.: The nature of endothelium derived vascular relaxant factor. Nature 308, 645– 647, 1984. 52 Hirashima, M., Sakata, K., Tashiro, K., et al.: Spontaneous production of eosinophil chemotactic factors by T lymphocytes from patients with subcutaneous angioblastic lymphoid hyperplasia with eosinophilia. Clin. Immunol. Immunopathol. 39, 231– 241, 1986. 53 Henderson, W. R., Harley, J. B. & Fauci, A. S.:Arachidonic acid metabolism in normal and hyper eosinophilic syndrome human eosinophils: generation of leukotrienes B4, C4, D4 and 15-lipoxygenase products. Immunology 51, 679– 686, 1984. 54 Henderson, W. R., Jörg, A. & Klebanoff, S. J.: Eosinophil perioxidase-mediated inactivation of leukotrienes B4, C4 and D4. J. Immunol. 128, 2609– 2613, 1982. 55 Henocq, E. & Vargaftig, B. B.: Accumulation of eosinophils in response to intracutaneous PAF-acether and allergens in man. Lancet 1, 1378– 1379, 1986. 56 Hirsch, J. G. & Hirsch, B. I: Paul Ehrlich and the discovery of the eosinophil. In A. A. F. Mahmoud & K. F. Austen, (eds.): The eosinophil in health and disease, pp. 3– 23, Grune & Stratton, New York , 1980. 57 Holgate, S. T., Church, M. K. Cushley, M. J., Robinson, C., Mann, J. S. & Howarth, P. H.: Pharmacological modulation of airway calibre and mediator release in human models of bronchial asthma. In: A. B. Kay, K. F. Austen & L. M. Lichtenstein, (eds.): Asthma: physiology, immunopharmacology and treatment, pp. 391– 415. Academic Press, London , 1984. 58 Horn, B. R., Robin, E. D. Theodore, J. & van Kessel, A.: Total eosinophil counts in the management of bronchial asthma. N. Engl. J. Med. 292, 1152– 1155, 1975. 59 Hunter, J. A., Finkbeiner, W. E., Nadel, J. A. Goetzl, E. J. & Holtzman, M. J.: Predominant generation of 151ipoxygenase metabolites of arachidonic acid by epithelial cells from human trachea. Proc. Natl. Acad. Sci. U.S.A. 82, 4633– 4637, 1985. 60 Joseph, M., Auriault, C., Capron, A., Voring, H. & Veins, P.: A new function for platelets: IgE-dependent killing of schistosomes. Nature 303, 810– 812, 1983. 61 Jouvin-March, E., Grzych, J. M., Boullet, C. Capron, M. & Benveniste, J.: Formation of PAF-acether by human eosinophils. Fed. Proc. 43, 1924 (Abstr.), 1984. 62 Kay, A. B.: Studies on eosinophil leucocyte migration II. Factors specifically chemotactic for eosinophils and neutrophils generated from guinea-pig serum by antigen-antibody complexes. Clin. Exp. Immunol. 7, 723– 727, 1970. 63 Kay, A. B.: Eosinophils as effector cells in immunity and hypersensitivity disorders. Clin. Exp. Immunol. 62, 1– 12, 1985. 64 Kay, A. B. & Austen, K. F.: The IgE-mediated release of an eosinophil leukocyte chemotactic factor from human lung. J. Immunol. 107, 899– 902, 1971. 65 Kay, A. B., Moqbel, R., Durham, S. R., et al.: Leucocyte activation initiated by IgE-dependent mechanisms in relation to helminthic parasitic disease and clinical models of asthma. Int. Arch. Allergy Appl. Immunol. 77, 69– 72, 1985. 66 Kay, A. B. & Walsh, G. M.: Chemotactic factor-induced enhancement of the binding of human immunoglobulin classes and subclasses to neutrophils and eosinophils. Clin. Exp. Immunol. 57, 729– 734, 1984. 67 Kay, A. B., Wardlaw, A. J., Collins, J. V., Dunnette, S. & Gleich, G. J.: Eosinophil and major basic protein in bronchoalveolar lavage in asthma: relationship to non specific hyperreactivity. J. Allergy Clin. Immunol. 77, 236 (Abstr.), 1986. 68 Kay, A. B., Wardlaw, A. J., Moqbel, R., Buchanan, D. R. & Cromwell, O.: Leucocytes and the asthma process. In: Allergy and inflammation. Academic Press, London (in press). 69 Kazura, J. W., Mahmoud, A. A. F., Karb, K. S. & Warren, K. S.: The lymphokine eosinophil stimulation promoter and human schistosomiasis mansoni. J. Infect. Dis. 132, 702– 706, 1975. 70 Kierszenbaum, F., Ackerman, S. J. & Gleich, G. J.: Destruction of bloodstream forms of Trypanosoma cruzi by eosinophil granule major basic protein. Am. J. Trop. Med. Hyg. 30, 775– 779, 1985. 71 Laitenen, L. A., Heino, M., Laitenen, A., Kava, T. & Haahtela, T.: Damage of the airway epithelium and bronchial reactivity in patients with asthma. Am. Rev. Respir. Dis. 131, 599– 606, 1985. 72 Lee, T., Hanahan, D. J. Malone, B., Roddy, L. L. & Wasserman, S. I.: I. Increased biosynthesis of platelet activating factor in activated human eosinophils. J. Biol. Chem. 259, 5526– 5530, 1984. 73 Lewis, R. A. & Austen, K. F.: The biologically active leukotrienes. Biosynthesis, metabolism, receptors, functions and pharmacology. J. Clin. Invest. 73, 889– 897, 1984. 74 Luksza, A. R. & Jones, D. K.: Comparison of whole blood eosinophil counts in extrinsic asthmatics with acute and chronic asthma. Br. Med. J. 285, 1229– 1231, 1982. 75 MacDonald, A. J., Moqbel, R., Wardlaw, A. J. & Kay, A. B.: Platelet activating factor (PAF-acether) enhances eosinophil cytotoxicity in vitro. J. Allergy Clin. Immunol. 77, 221 (Abstr.), 1986. 76 McLaren, D. J., McKean, J. R., Olsson, I., Venge, P. & Kay, A. B.: Morphological studies on the killing of schistosomula of Schistosoma mansoni by human eosinophil and neutrophil cationic proteins in vitro. Parasit.orphological studies on the killing of schistosomula of Schistosoma mansoni by human eosinophil and neutrophil cationic proteins in vitro. Parasit.ro. Parasit.o. Parasit.. Parasit.arasit. Immunol. 3, 359– 373, 1981. 77 McManus, L. M., Hanahan, D. J. & Pinckard, R. N.:Human platelet stimulation by acetyl glyceryl ether phosphorylcholine. J. Clin. Invest. 67, 903– 906, 1981. 78 Melewicz, F. M. & Spiegelberg, H. L.: Fc receptors for IgE on a subpopulation of human peripheral blood monocytes. J. Immunol. 125, 1026– 1031, 1980. 79 Metzger, H. & Bach, M. K.: The receptor for IgE on mast cells and basophils, studies on IgE binding and on the structure of the receptor. In M. K. Bach, (ed.): Immediate hypersensitivity, pp. 561– 588. Marcel Dekker, New York , 1978. 80 Metzger, W. J., Hunninghake, G. W. & Richerson, H. B.: Late asthmatic response: Inquiry into mechanisms and significance. Clin. Rev. Allergy 3, 145– 165, 1985. 81 Murphy, K. R., Irvin, C. G., Glezin, L. S., March, W. R. & Larsen, G. L.: The effect of polymorphonuclear leucocyte depletion on the late asthmatic response and changes in bronchial hyperreactivity. Am. Rev. Respir. Dis. 131, A6 (Abstr.), 1985. 82 Nagy, L., Lee, T. H., Goetzl, E. J., Pickett, W. C. & Kay, A. B.: Complement receptor enhancement and chemotaxis of human neutrophils and eosinophils by leukotrienes and other lipoxygenase products. Clin. Exp. Immunol. 47, 541– 547, 1982. 83 Naylor, B.: The shedding of the mucosa of the bronchial tree in asthma. Thorax 17, 69– 72, 1962. 84 NHLBI Workshop Summaries: Summary and recommendations of a workshop on the investigative use of fibreoptic bronchoscopy and bronchoalveolar lavage in asthmatics. Am. Rev. Respir. Dis. 132, 180– 182, 1985. 85 Nicola, N. A., Metcalfe, D., Johnson, G. R. & Burgers, A. W.: Preparation of colony stimulating factors from human placental conditioned medium. Leukreparation of colony stimulating factors from human placental conditioned medium. Leukum. Leukm. Leuk. Leukeuk Res. 2, 313, 1978. 86 O'Donnell, M. C., Ackerman, S. J., Gleich, G. J. & Thomas, L. L.: Activation of basophil and mast cell histamine release by eosinophil granule major basic protein. J. Exp. M. 157, 1981–1991, 1983. 87 O'Flaherty, J. T. & Wykle, R. L.: Biology and biochemistry of platelet-activating factor. Clin. Rev. Allergy 1, 353– 367, 1983. 88 Parish, W. E.: Substance that attract eosinophils in vitro and in vivo and that elicit blood eosinophilia. In E. Salter, (ed.): Chemotaxis: its biology and biochemistry, pp. 233. S. Karger, Basel , 1974. 89 Parish, W. E. & Luckhurst, E.: Eosinophilia VI, spontaneous synthesis of chemokinetic, chemotactic, complement receptor-inducing activities for eosinophils by bronchial T lymphocytes of asthmatic-bronchitis patients. Clin. Allergy 12, 475– 488, 1982. 90 Prin, L., Capron, M., Tonnel, A. B., Blentry, O. & Capron, A.: Heterogeneity of human peripheral blood eosinophils: variability in cell density and cytotoxic ability in relation to the level and origin of hyper-eosinophilia. Int. Arch. Allergy Appl. Immunol. 72, 336– 346, 1983. 91 Richerson, H. B., Metzger, W. J. & Hunninghake, G. W.: Experimental models of bronchial asthma in man and the rabbit. In A. B. Kay, (ed.): Asthma: clinical pharmacology and therapeutic progress, pp. 23– 32. Blackwell Scientific, Oxford , 1986. 92 Salari, H., Borgeat, P., Fournier, M., Herbert, J., Pelletier, G.: Studies on the release of leukotrienes and histamine by human lung parenchymal and non-immunologic stimulation. J. Exp. Med. 162, 1904– 1915, 1985. 93 Sanderson, C. J., Waren, D. J. & Straten, M.: Identification of a lymphokine that stimulates eosinophil differentiation in vitro: Its relationship to Interleukin 3, and functional properties of eosinophils produced in cultures. J. Exp. Med. 162, 60– 74, 1985. 94 Schleimer, R. P., MacGlashan, D. W. Jr., Peters, S. P., Pinckard, R. N., Adkinson, N. F. & Lichtenstein, L. M.: Characterization of inflammatory mediator release from purified human lung mast cells. Am. Rev. Respir. Dis. 133, 614– 617, 1986. 95 Schleimer, R. P., Schulman, E. S., MacGlashan, D. W. Jr. et al.: Effect of dexamethasone on mediator release from human lung fragments and purified human lung mast cells. J. Clin. Invest. 71, 1830– 1835, 1983. 96 Shaw, J. O., Pinckard, R. N., Ferrigni, K. S., McManus, L. M. & Hanahan, D. J.: Activation of human neutrophils with l-0-hexadecyl/octadecyl-2-acet-yl-sn-glyceryl-3-phosphorylcholine (platelet activating factor). J. Immunol. 127, 1250– 1255, 1981. 97 Shaw, R. J., Walsh, G. M., Cromwell, O., Moqbel, R., Spry, C. J. F. & Kay, A. B.: Activated human eosinophils generate SRS-A leukotrienes following physiological (IgG-dependent) stimulation. Nature 316, 150– 152, 1985. 98 Shaw, R. J., Cromwell, O. & Kay, A. B.: Preferential generation of leukotriene C4 by human eosinophils. Clin. Exp. Immunol. 56, 716– 722, 1984. 99 Slovick, F. T., Abboud, C. N., Brennan, J. K., & Lichtman, M. A.: Modulation of in vitro eosinophil progenitors by hydrocortisone: role of accessory cells and interleukins. Blood 66, 1072– 1079, 1985. 100 Solley, G. O., Gleich, G. J., Jordan, R. E., Schroeter, A. L.: The late phase of the immediate wheal and flare skin reaction. J. Clin. Invest. 38, 408– 420, 1976. 101 Spry, C. J. F.: Synthesis and secretion of eosinophil granule substances. Immunol. Today 6, 332– 335, 1985. 102 Prin, L., Capron, M., Gossett, P., et al.: Eosinophilic lung disease: immunological studies of blood and alveolar eosinophils. Clin. Exp. Immunol. 63, 249– 257, 1986. 103 Taylor, K. J. & Luksza, A. R.: Peripheral blood eosinophil count and bronchial hyperreactivity. Thorax 41, 241 (Arbstr.), 1986. 104 Tomioka, M., Ida, S., Shindoh, Y., Ishihara, T. & Takishima, T.: Mast cells in bronchoalveolar lumen of patients with bronchial asthma. Am. Rev. Respir. Dis. 129, 1000– 1005, 1984. 105 Turnbull, L. W. & Kay, A. B.: Eosinophils and mediators of anaphylaxis. Histamine and imidazole acetic acid as chemotactic agents for human eosinophil leucocytes. Immunology 31, 797– 802, 1976. 106 Vadas, M. A., David, J. R., Butterworth, A., Pisani, N. T. & Siongok, T. A.: A new method for the purification of human eosinophils and neutrophils and a comparison of the ability of these cells to damage schistosomula of Schistosoma mansoni. J. Immunol. 122, 1228– 1236, 1979. 107 Vadas, M. A., Nicola, N., Lopez, A. F., Metcalfe, D., Johnson, G. & Pereire, A.: Mononuclear cell-mediated enhancement of granulocyte function in man J. Immunol. 133, 202– 207, 1984. 108 Veith, M. A. & Butterworth, A. E.: Enhancement of human eosinophil-mediated killing of Schistosoma mansoni larvae by mononuclear cell production in vitro. J. Exp. Med. 157, 1828– 1843, 1983. 109 Wadee, A. E. & Sher, R.: The effect of a soluble factor released by sensitized mononuclear cells incubated with S. haematobium ova on eosinophil migration. Immunology 41, 989– 995, 1980. 110 Walsh, G. M. & Kay, A. B.: Binding of Immunoglobulin classes and subclasses to human neutrophils and eosinophils. Clin. Exp. Immunol. 63, 466– 472, 1986. 110 Walsh, G. M., Moqbel, R., Wardlaw, A. J. & Kay, A. B.: Enhancement of IgG and IgE receptors and other inflammatory mediators. J. Allergy Clin. Immunol. 79, 172(abstr.), 1987. 111 Wardlaw, A. J., Cromwell, O., Celestino, D., et al.: Morphological and secretory properties of bronchoalveolar lavage mast cells in respiratory diseases. Clin. Allergy 16, 163– 173, 1986. 112 Wardlaw, A. J., Moqbel, R., Cromwell, O. & Kay, A. B.: Platelet activating factor. A potent chemotactic and chemokinetic factor for human eosinopils. J. Clin. Invest. 78, 1701– 1706, 1986. 113 Wasserman, S. I., Goetzl, E. J. & Austen, K. F.:Preformed eosinophil chemotactic factor of anaphylaxis(ECF-A). J. Immunol. 112, 351– 358, 1974. 114 Wasserman, S. I., Goetzl, E. J. & Austen, K. F.: Inactivation of slow reacting substance of anaphylaxis by human eosinophil arylsulfatase. J. Immunol. 114, 645– 649, 1975. 115 Wassom, D. G. & Gleich, G. J.: Damage to Trichinella spiralis newborn larvae by eosinophil major basic protein. Am. J. Trop. Hyg. 28, 860– 863, 1979. 116 Weller, P. F.: Eosinophilia. J. Allergy Clin. Immunol. 73, 1– 9, 1984. 117 Weller, P. F., Goetzl, E. J.: The regulatory and effector roles of eosinophils. Adv. Immunol. 27, 339– 371, 1979. 118 Weller, P. F., Goetzl, E. J., Austen, K. F.: Identification of human eosinophil lysophospholipase as the constituent of Charcot-Leyden crystals. Proc. Natl. Acad. Sci. U.S.A. 77, 7440– 7443, 1980. 119 Weller, P. F., Lee, C. N., Foster, D. W., Corey, E. J., Austen, K. F. & Lewis, R. A.: Generation and metabolism of 5-lipoxygenase pathway leukotrienes by human eosinophils: predominant production of leukotriene C4. Proc. Natl, Acad. Sci. U.S.A. 80, 7625– 7630, 1983. 120 Weller, P. F. Wasserman, S. I. & Austen, K. F.: Selected enzymes preferentially present in the eosinophil. In A. A. F. Mahmoud & K. F. Austen, (eds.): The eosinophil in health and disease, pp. 115– 120. Grune & Stratton, New York , 1980. 121 Zeigler, R. S., Yurdin, D. L., Golten, H. R.: Histamine metabolism, C1 cellular and subcellular localization of the catabolic enzymes, histamine methyl transferase in human leucocytes. J. Allergy Clin. Immunol. 58, 172– 179, 1976. Citing Literature Volume42, Issue5July 1987Pages 321-335 ReferencesRelatedInformation
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