Artigo Revisado por pares

Congenital Malformations Produced by Injecting Azo Blue into Pregnant Rats.

1954; SAGE Publishing; Volume: 85; Issue: 2 Linguagem: Inglês

10.3181/00379727-85-20867

ISSN

1535-3702

Autores

James G. Wilson,

Tópico(s)

Chemical Analysis and Environmental Impact

Resumo

The injection of 1 cc of a 1% aqueous solution of the diazo dye azo blue into female rats on the 7th, 8th and 9th days of pregnancy resulted in congenital malformations in 59% of living fetuses removed on the 20th day of gestation. The incidence was higher than that obtained with trypan blue (49%) under the same conditions, but the types of malformations were similar.

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