Acquired Hypocalciuric Hypercalcemia Due to Autoantibodies against the Calcium-Sensing Receptor
2004; Massachusetts Medical Society; Volume: 351; Issue: 4 Linguagem: Inglês
10.1056/nejmoa040008
ISSN1533-4406
AutoresJ. Carl Pallais, Olga Kifor, Yi‐Bin Chen, David M. Slovik, Edward M. Brown,
Tópico(s)Parathyroid Disorders and Treatments
ResumoA complex homeostatic system involving the interplay of bone, the kidneys, and the intestines maintains extracellular calcium levels within a relatively narrow range. This article describes a patient with autoimmune hyperparathyroidism and hypocalciuric hypercalcemia caused by IgG4 autoantibodies directed against the calcium-sensing receptor. The patient's hypercalcemia and elevated parathyroid hormone levels responded to the administration of glucocorticoids.
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