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Powder dynamic contact angle data in the pharmaceutical industry

1999; Elsevier BV; Volume: 2; Issue: 3 Linguagem: Inglês

10.1016/s1461-5347(99)00129-7

1879-0186

Xavier Pépin, Sylvène Blanchon, Guy Couarraze,

Adsorption, diffusion, and thermodynamic properties of materials

Formulation scientists generate physicochemical data that are used in process modelling and in the prediction of end-product quality. In this respect, contact angles are of particular importance as the surface energy of substances influences their processability and bioavailability. Dynamic contact angle (DCA) analysis represents a straightforward wettability assay. Now fully adapted to powders, DCA analysis also proves to be more efficient than other methods for wettability determination.