Portal de Periódicos da CAPES

3-(Pyridine-4-thione)BODIPY as a chemodosimeter for detection of Hg(II) ions

2012; Elsevier BV; Volume: 95; Issue: 1 Linguagem: Inglês

10.1016/j.dyepig.2012.03.015

1873-3743

Tamanna K. Khan, Mangalampalli Ravikanth,

Advanced biosensing and bioanalysis techniques

A new chemodosimeter for detection of Hg(II) ions based on boron-dipyrromethene (BODIPY) is developed. The 3-(pyridine-4-thione)BODIPY was synthesized in high yield by treating 3-(pyridine-4-one)BODIPY with Lawesson's reagent. The 3-(pyridine-4-thione) BODIPY was confirmed by HR-MS mass, 1H, 1H–1H COSY, 19F and 11B NMR techniques. In 1H NMR, the protons which are adjacent to sulfur in 3-(pyridine-4-thione)BODIPY showed ∼1 ppm downfield shift compared to equivalent protons in 3-(pyridine-4-one)BODIPY. The absorption and electrochemical properties experienced slight changes in 3-(pyridine-4-thione)BODIPY compared to 3-(pyridine-4-one)BODIPY. The compound 3-(pyridine-4-thione)BODIPY is very weakly fluorescent compared to 3-(pyridine-4-one)BODIPY. Furthermore, 3-(pyridine-4-thione)BODIPY can be used as an exclusive chemodosimeter for Hg2+ ion as it shows significant enhancement in the fluorescence intensity and a dramatic visible color change from pink to fluorescent green in the presence of Hg(II) ions.