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MONOCLONAL ANTIBODIES AS TOOLS IN GENETIC STUDIES ON CARBOHYDRATE BLOOD GROUP ANTIGENS

1990; Wiley; Volume: 17; Issue: 4-5 Linguagem: Inglês

10.1111/j.1744-313x.1990.tb00879.x

1744-313X

Winifred M. Watkins,

Monoclonal and Polyclonal Antibodies Research

International Journal of ImmunogeneticsVolume 17, Issue 4-5 p. 259-276 MONOCLONAL ANTIBODIES AS TOOLS IN GENETIC STUDIES ON CARBOHYDRATE BLOOD GROUP ANTIGENS W. M. Watkins, Corresponding Author W. M. Watkins MRC Clinical Research Centre, Watford Road, Harrow, Middlesex, U.K.Winifred M. Watkins, MRC Clinical Research Centre, Watford Road, Harrow, Middlesex HA1 3UJ, U.K.Search for more papers by this author W. M. Watkins, Corresponding Author W. M. Watkins MRC Clinical Research Centre, Watford Road, Harrow, Middlesex, U.K.Winifred M. Watkins, MRC Clinical Research Centre, Watford Road, Harrow, Middlesex HA1 3UJ, U.K.Search for more papers by this author First published: August 1990 https://doi.org/10.1111/j.1744-313X.1990.tb00879.xCitations: 10AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References Amos, D.B. & Kostyu, D.D. (1980) HLA- a central immunological agency of man. Advances in Humon Genetics, 10, 137. CASPubMedGoogle Scholar Anstee, D.A. (1990) Blood group active surface molecules of the human red blood cell. Vox Sunguinis, 58, 1. 10.1111/j.1423-0410.1990.tb02049.x CASPubMedWeb of Science®Google Scholar Badet, J., Ropars, C., Cartron, J.-P., Doinel, C. & Salmon, C. (1976) Groups of α-D-galactosyltransferase activity in the sera of individuals with normal B phenotype. II. Relationship between transferase activity and red cell agghtinability. Vox Sunguinis, 30, 105. 10.1111/j.1423-0410.1976.tb02800.x CASPubMedWeb of Science®Google Scholar Beck, M.L., Hardman, J.T. & Henry, R. (1986) Reactivity of a licensed murine monoclonal anti-A reagent with group B cells. Trunsfusion, 26, 572. Web of Science®Google Scholar Beck, M.L., Yates, A.D., Hardman, J.T. & Kowalski, M.A. (1987) Consequences of overlapping substrate specificity of glycosyltransferases. Transfusion, 27, 572. Google Scholar Bernstein, F. (1924) Ergebnisse einer biostatischen zusammenfassenden betrachtung uber die erblichen blutstruckturendes blutes. Klinicke Wochenschrift, 3, 1495. 10.1007/BF01736255 Google Scholar Breimer, M.E. (1980) Adaptation of mass spectrometry for the analysis of tumour antigens as applied to blood group glycolipids of a human gastric carcinoma. Cancer Research, 40, 897. CASPubMedWeb of Science®Google Scholar Breimer, M.E. & Jorvall, P.-A. (1985) Structural characterisation of a blood group A heptaglycosylceramide with globo-series structure. FEBS Letters, 179, 165. 10.1016/0014-5793(85)80213-1 CASPubMedWeb of Science®Google Scholar Cartron, J.-P., Badet, J., Mulet, C. & Salmon, C. (1978) Study of the a-N-acetylgalactosaminyltransferase in sera and red cell membranes of human subgroups. Journal of Immunogenetics, 5, 107. 10.1111/j.1744-313X.1978.tb00635.x CASPubMedWeb of Science®Google Scholar Cepellini, R. (1955) On the genetics of secretion and Lewis characters: a family study. Proceedings of the Vth Congress of the International Society of Blood Transfusion. Paris, 1954, p. 201. Google Scholar Childs, R.A., Berger, E.G., Thorpe, S. J., Aegerter, E. & Feizi, T. (1986) Blood group related carbohydrate antigens are expressed on human milk galactosyltransferase and are immunogenic in rabbits. Biochemical Journal, 238, 605. 10.1042/bj2380605 CASPubMedWeb of Science®Google Scholar Clausen, H. & Hakomori, S. (1989) ABH and related histo-blood group antigens: Immunochemical differences in carrier isotypes and their distribution. Vox Sanguinis, 56, 1. 10.1111/j.1423-0410.1989.tb03040.x CASPubMedWeb of Science®Google Scholar Clausen, H., Levery, S.B., Nudelman, E., Tsuchiya, S. & Hakomori, S. (1985) Repetitive A epitope (type 3 chain A) defined by blood group A1-specific monoclonal antibody TH-1: Chemical basis of qualitative A1 and A, distinction. Proceedings of the National Academy of Sciences, U.S.A., 82, 1199. 10.1073/pnas.82.4.1199 CASPubMedWeb of Science®Google Scholar Clausen, H., Hakomori, S., Graem, N. & Dabelsteen, E. (1986) Incompatible A antigen expressed in tumours of blood group O and B individuals; immunochemical, immunohistological and enzymatic characterization. Journal of Immunology, 136, 326. CASPubMedWeb of Science®Google Scholar Cook, G.A., Greenwell, P. & Watkins, W.M. (1982) A rabbit antibody to the blood group A gene specified α-3-N-acetylgalactosaminyltransferase. Biochemical Society Transactions, 10, 446. 10.1042/bst0100446 CASGoogle Scholar Denk, H., Tappeiner, G., Davidovits, A., Eckerstorfer, R. & Holzner, J.H. (1974) Carcinoembryonic antigen and blood group substances in carcinomas of stomach and colon. Journal of the National Cancer Institute, 53, 933. PubMedWeb of Science®Google Scholar Donald, A.S.R. (1981) A-Active trisaccharides isolated from A1 and A2 blood group specific glycoproteins. European Journal of Biochemistry, 120, 243. 10.1111/j.1432-1033.1981.tb05695.x CASPubMedWeb of Science®Google Scholar Dungern, E. von. & Hirszfeld, L. (1910) Ueber verebung gruppenspezifischer struckturen des blutes. Zeitschrift Immunotatsforschung, 6, 284. Google Scholar Eto, T., Ichikawa, Y., Nishimura, K., Ando, S. & Yamakawa, T. (1968) Chemistry of lipid of post-hemolytic residue of erythrocytes XVI. Occurrence of ceramide pentasaccharide in the membranes of erythrocytes and reticulocytes. Journal of Biochemistry (Tokyo), 64, 205. 10.1093/oxfordjournals.jbchem.a128881 CASPubMedWeb of Science®Google Scholar Feizi, T. (1981) Blood group Ii system. A carbohydrate antigen system defined by naturally monoclonal or oligoclonal auto antibodies of man. Immunological Communications, 10, 127. 10.3109/08820138109050693 CASPubMedWeb of Science®Google Scholar Feizi, T. (1985) Demonstration by monoclonal antibodies that carbohydrate structures of glycoproteins and glycolipids are oncodevelopmental antigens. Nature, 314, 53. 10.1038/314053a0 CASPubMedWeb of Science®Google Scholar Fredrick, J., Hunter, J., Greenwell, P., Winter, K. & Gottschall, J.L. (1985) The A1 B phenotype expressed as A2B on the red cells of individuals with strong B gene-specific transferases, Transfusion, 25, 30. 10.1046/j.1537-2995.1985.25185116498.x CASPubMedWeb of Science®Google Scholar Goldstein, J., Lenny, L., Davies, D. & Voak, D. (1989) Further evidence for the presence of A antigen on group B erythrocytes through the use of specific exo-glycosidases. Vox Sanguinis, 57, 142. 10.1111/j.1423-0410.1989.tb01152.x PubMedWeb of Science®Google Scholar Goor, H.C., Hounsell, E.F., Picard, J.K., Lowe, A.D., Voak, D. & Lennox, E.S. (1985) Differing reactions of monoclonal anti-A antibodies with oligosaccharides related to blood group A. Journal of Biological Chemistry, 260, 13218. PubMedWeb of Science®Google Scholar Greenwell, P., Yates, A.D & Watkins, W.M. (1979) Blood group A synthesizing activity of the blood group B gene specified α-3-galactosyl transferase. In Glycoconjugates (Ed. by R. Schauer, R. Boer, E. Buddecke, M.F. Kramer & J. Vliegenthart). p. 268. Thieme, Stuttgart . Google Scholar Greenwell, P., Yates, A.D. & Watkins, W.M. (1986) UDP-N-acetylgalactosamine as a donor substrate for the glycosyltransferase encoded by the B gene at the human blood group ABO locus. Carbohydrate Research, 149, 149. 10.1016/S0008-6215(00)90375-6 CASPubMedWeb of Science®Google Scholar Greenwell, P. & Watkins, W.M. (1987) Demonstration of fucosyl 1–2-galactoside α-I-3-N-acetylgalactos-aminyltransferase activity in the serum and tissues of blood group O individuals. Proceedings of the 9th International Symposium Glycoconjugates. Lille, France, Abstract E 34. Google Scholar Greenwell, P., Edwards, Y.H., Williams, J. & Watkins, W.M. (1987) Approaches to cloning the genes at the human blood group ABO locus. Biochemical Society Transactions, 15, 601. 10.1042/bst0150601 CASPubMedWeb of Science®Google Scholar Grubb, R. (1951) Observations on the human group system Lewis. Acta Pathological Microbiology Scandinavica, 28, 61. 10.1111/j.1699-0463.1951.tb05004.x PubMedWeb of Science®Google Scholar Hakkinen, I. (1970) A-like blood group antigen in gastric cancer cells of patients of blood groups O and B. Journal of the National Cancer Institute, 44, 1183. PubMedWeb of Science®Google Scholar Hakomori, S. (1978) Isolation of blood group active ABH glycolipids from human erythrocyte membranes. Methods in Enzymology, 50, 207. 10.1016/0076-6879(78)50021-9 PubMedGoogle Scholar Hakomori, S. (1984a) Monoclonal antibodies directed to cell surface carbohydrates. In Monoclonal antibodies and functional cell lines (Ed. by Bechtol Kennett & McKearn), p. 67, Plenum Press, New York . 10.1007/978-1-4684-4673-9_4 Google Scholar Hakomori, S. (1984b) Tumour associated carbohydrate antigens. Annual Reoiew of Immunology, 2, 103. 10.1146/annurev.iy.02.040184.000535 CASPubMedWeb of Science®Google Scholar Harris, H. (1975) Principles of Human Biochemical Genetics, 2nd edition. North-Holland, Amsterdam . Google Scholar Jeffreys, A.J., Wilson, V. & Thein, S.V. (1985) Hypervariable 'minisatellite' regions in human DNA. Nature, 324, 67. 10.1038/314067a0 Web of Science®Google Scholar Kannagi, R., Levery, S.B. & Hakomori, S. (1984) Blood group H antigen with globo-series structure: Isolation and characterization from human blood group O erythrocytes. FEBS Letters, 175, 397. 10.1016/0014-5793(84)80776-0 CASPubMedWeb of Science®Google Scholar Kapadia, A., Feizi, T., Jewell, D., Keeling, J. & Slavin, G. (1981) Immunocytochemical studies of blood group A, H, I and i antigens in gastric mucosae of infants with normal gastric histology and of patients with gastric carcinoma and chronic benign peptic ulcer. Journal of Clinical Pathology, 34, 320. 10.1136/jcp.34.3.320 CASPubMedWeb of Science®Google Scholar Karlsson, K.A. (1978) Glycolipid patterns of blood and other tissues. In: The XVfh Congress of the International Society of Blood Transfusion. Paris, 1978, Abstract p. 164. Google Scholar Karlssson, K.-A. & Larson, G. (1981) Molecular characterisation of cell surface antigens of foetal tissue: detailed analysis of glycosphingolipids of meconium of a human O Le(a-b +) secretor. Journal of Biological Chemistry, 256, 3512. PubMedWeb of Science®Google Scholar Kay, H. E. M. & Wallace, D.M. (1961) A and B antigens of tumours arising from urinary epithelium. Journal of the National Cancer Institute, 26, 1349. CASPubMedWeb of Science®Google Scholar Kobata, A. (1972) Oligosaccharides from human milk. Methods in Enzymology, 28, 262. 10.1016/0076-6879(72)28026-0 Google Scholar Kohler, G. & Milstein, C. (1975) Continuous cultures of fused cells secreting antibody of predefined specificity Nature, 256, 495. 10.1038/256495a0 CASPubMedWeb of Science®Google Scholar Koscielak, J., Miller-Podraza, J. & Zdebska, E. (1978) Isolation of polyglycosylceramides with A,B,H and I blood group activities. Methods in Enzymology, 50, 211. 10.1016/0076-6879(78)50022-0 CASPubMedGoogle Scholar Koscielak, J., Zdbeska, E., Wilcznska, Z., Miller-Podraza, H. & Dzierzkowa-Borodej, W. (1979) Immunochemistry of Ii-active glycosphingolipids of erythrocytes. European Journal of Biochemistry, 96, 331. 10.1111/j.1432-1033.1979.tb13044.x CASPubMedWeb of Science®Google Scholar Landsteiner, K. (1900) Zur kenntnis der antifermentativen, lytischen und agglutininierenden wirkungen des blutserum und der lymphe. Zentralblat Bakteriologie, 21, 357. Google Scholar Lloyd, K.O., Kabat, E.A. & Licerio, E. (1968) Immunochemical studies on blood groups. XXXVIII. Structures and activities of oligosaccharides produced by alkaline degradation of blood group Lewisa substance. Proposed structure of the carbohydrate chains of human blood group A, B, H, Lea and Leb substances. Biochemistry, 5, 1489. 10.1021/bi00869a007 PubMedWeb of Science®Google Scholar Lundblad, A. (1978) Oligosaccharides from human urine. Methods in Enzymology, 50, 226. 10.1016/0076-6879(78)50025-6 CASPubMedGoogle Scholar Marr, A.M.S., Donald, A.S.R., Watkins, W.M. & Morgan, W.T.J. (1967) Molecular and genetic aspects of human blood group Leb specificity. Nature, 215, 1345. 10.1038/2151345a0 CASPubMedWeb of Science®Google Scholar Morgan, W.T.J. (1960) A contribution to human biochemical genetics; the chemical basis of blood group specificity. Proceedings of the Royal Society, Series B, 151, 308. 10.1098/rspb.1960.0002 CASPubMedWeb of Science®Google Scholar Morgan, W.T.J. & Watkins, W.M. (1969) Genetic and biochemical aspects of human blood group A-, B-, H-, Lea and Leb-specificity. British Medical Journal, 25, 30. PubMedWeb of Science®Google Scholar Oriol, R., Le Pendu, J. & Mollicone, R. (1986) Genetics of ABO, H, Lewis, X and related antigens. Vox Sanguinis, 51, 161. 10.1111/j.1423-0410.1986.tb01946.x CASPubMedWeb of Science®Google Scholar Ørntoft, T., Nielsen, M. J. S., Wolf, H. et al.(1987) Blood group ABO and Lewis antigen expression during neoplastic progression of human urothelium. Cancer (Philadelphia), 60, 2641. 10.1002/1097-0142(19871201)60:11 3.0.CO;2-5 CASPubMedWeb of Science®Google Scholar Ørntoft, T., Wolf, H. & Watkins, W.M. (1988) Activity of the human blood group ABO, Se, H, Le and X gene encoded glycosyltransferases in normal and malignant bladder urothelium. Cancer Research, 48, 4421. Google Scholar Ørntolf, T. F., Greenwell, P., Clausen, H. & Watkins, W.M. (1990) Regulation of the oncodevelopmental expression of type 1 chain ABH and Leb blood group antigens in human colon by α-2-L-fucosylation. Gut, (in press). Google Scholar Paihter, T.J., Watkins, W.M. & Morgan, W.T.J. (1965) Serologically active fucose-containing oligosaccharides isolated from human blood-group A and B substances. Nature, 199, 282. 10.1038/199282a0 PubMedWeb of Science®Google Scholar Paulson, J. & Colley, K.J. (1989) Clycosyltransferases; Structure, localisation and control of cell type-specific glycosylation. Journal of Biological Chemistry, 264, 17615. CASPubMedWeb of Science®Google Scholar Piller, F., Schenkel-Brunner, H. & Tuppy, H. (1979) Altered biosynthesis of blood group related antigens in neoplastic colon mucosa. Proceedings of the 5th International Symposium on Glycoconjugates (Ed. by R. Schauer, P. Boer, E. Buddecke, M.F. Kramer, J.F.G. Vliegenthart and H. Wiegandt) p. 639, Thieme, Stuttgart . Google Scholar Race, R.R. & Sanger, R. (1975) Blood Groups in Man, 6th edition, Blackwell Scientific Publications, Oxford . Google Scholar Rajan, V.P., Larsen, R.D., Ajmera, S., Ernst, L. & Lowe, J.B. (1989) A cloned human DNA restriction fragment determines expression of a GDP-L-fucose β-D-galactoside 2–α-L-Fucosyltransferase in transfected cells. Journal of Biological Chemistry, 264, 11158. CASPubMedWeb of Science®Google Scholar Rettig, W.J. & Old, L.J. (1989) Immunogenetics of human cell surface differentiation. Annual Reoiew of Immunology, 7, 481. 10.1146/annurev.iy.07.040189.002405 CASPubMedWeb of Science®Google Scholar Roth, J., Greenwell, P. & Watkins, W.M. (1988) Immunolocalisation of blood group A gene specified al,3N-acetylgalactosaminyltransferase and blood group A substance in the transtubular network of the Golgi apparatus and mucus of intestinal goblet cells. European Journal of Cell Biology, 46, 105. CASPubMedWeb of Science®Google Scholar Rydberg, L., Breimer, M.E., Samuelsson, B.E. & Brynger, H. (1987) Blood group ABO-incompatible (A2 to O) kidney transplantation in human subjects: A clinical, serologic, and biochemical approach. Transplantation Proceedings, 29, 4528. Google Scholar Sabharwal, H., Chester, M.A., SIoblad, S. & Lundblad, A. (1983) Blood group specific oligosaccharides in faeces of breast-fed children. Proceedings of the 7th International Symposium on Glycoconjugates, Lund (Ed. by M.A. Chester, D. Heinegard, A. Lundblad & S. Svensson), p. 221. Secretariat, Lund . Google Scholar Schachter, H., Michaels, M.A., Tilley, C.A., Crookston, M.C. & Crookston, J.H. (1973) Qualitative differences in the N-acetylgalactosaminyltransferases produced by human A1 and A2 genes. Proceedings of the National Academy of Sciences. U.S.A., 70, 220. 10.1073/pnas.70.1.220 CASPubMedWeb of Science®Google Scholar Sonneborn, H. & Voak, D. (1988) Monoclonal antibodies detect overlapping specificities of A and B glycosyltransferases. ISH Congress, Milan. Google Scholar Szulman, A.E. (1960) The histological distribution of blood group substances A and R in man. Journal of Experimental Medicine, 111, 785. 10.1084/jem.111.6.785 CASPubMedWeb of Science®Google Scholar Szulman, A.E. (1962) The histological distribution of blood group substances in man as disclosed by immunofluorescence II. The H antigen and its relation to A and B antigen. Journal of Experimental Medicine, 115, 977. 10.1084/jem.115.5.977 CASPubMedWeb of Science®Google Scholar Szulman, A.E. & Marcus, D.M. (1973) The histological distribution of blood group substances in man as disclosed by immunofluoresence, VI. The Lea and Leb antigens during fetal development. Loboratory Investigation, 28, 565. CASPubMedWeb of Science®Google Scholar Takisawa, N. & Iseki, S. (1981) Immunological specificity of blood group glycosyltransferase. Proceedings of the 6th International Symposium on Glycoconjugates, Tokyo. (Ed. by T. Yamakawa, T. Osawa & S. Handa) p. 379, Japanese Scientific Societies Press, Tokyo . Google Scholar Tippett, P. (1983) Blood group chimeras: A review. Vox Sanguinis, 44, 333. 10.1111/j.1423-0410.1983.tb03657.x PubMedWeb of Science®Google Scholar Tippett, P. (1986) Contributions of monoclonal antibodies to understanding one new and some old blood group systems. In; Red Cell antigens and antibodies, (Ed. by G. Garratty). American Association of Blood Banks, Arlington , VA. Google Scholar Topping, M. & Watkins, W.M. (1975) Isoelectric points of the human blood group A1, A2 and B gene-associated glycosyltransferases in ovarian cyst fluids and serum. Biochemical and Biophysical Research Communications, 64, 89. 10.1016/0006-291X(75)90223-5 CASPubMedWeb of Science®Google Scholar Voak, D. (1987) The evaluation of monoclonal anti-A antibodies for use as blood grouping reagents. Revue Francais de Transfusion et Immuno-hematologie, 30, 363. 10.1016/S0338-4535(87)80093-4 CASPubMedWeb of Science®Google Scholar Voak, D. (1989) Monoclonal antibodies in blood group serology. Transfusion Science, 10, 5. 10.1016/0955-3886(89)90004-0 Web of Science®Google Scholar Watanabe, K., Hakomori, S., Childs, R.A. & Feizi, T. (1979) Characterization of blood group I-active ganglioside. Structural requirements for I and i specificities. Journal of Biological Chemistry, 254, 3221. CASPubMedWeb of Science®Google Scholar Watkins, W.M. (1980) Biochemistry and genetics of the ARO, Lewis and P blood group systems. Aduances in Human Genetics, 10, 1. CASPubMedGoogle Scholar Watkins, W.M. & Greenwell, P. (1983) Molecular basis of human red cell antigens. Proceedings of the 10th International Congress of the Society for Forensic Haemogenetics, Munich, p. 67. Google Scholar Watkins, W.M., Greenwell, P., Yates, A.D. & Johnson, P.H. (1988) Regulation of expression of carbohydrate blood group antigens. Biochimie, 70, 1597. 10.1016/0300-9084(88)90295-7 CASPubMedWeb of Science®Google Scholar White, T., Mandel, U., Ørntoft, T. F., Dabelsteen, E., Karkov, J., Kubeja, M., Hakomori, S. & Clausen, H. (1990) Murine monoclonal antibodies directed to the human histo-blood group A transferase (UDP-GalNAc:Fucαl-2Galαl-3-N-acetylgalactosaminyltransferase) and the presence therein of N-linked histo-blood group A determinant. Biochemistry, 29, 2740. 10.1021/bi00463a017 CASPubMedWeb of Science®Google Scholar Wiener, AS. (1943) Blood Groups and Transfusion, Thomas Springfield, Illinois , p. 332. Google Scholar Yamamoto, F., Clausen, H., White, T., Marken, J. & Hakomori, S. (1990a) Molecular genetic basis of the histo-blood group ABO system. Nature, 345, 229. 10.1038/345229a0 CASPubMedWeb of Science®Google Scholar Yamamoto, F., Marken, J., Tsuji, T., White, T., Clausen, H. & Hakomori, S. (1990b) Cloning and characterisation of DNA complementary to human UDP-Ga 1NAc:Fuc 1–2Gal 1–3GalNAc transferase (Histo-blood group A transferase) mRNA. Journal of Biologicul Chemistry, 265, 1146. CASPubMedWeb of Science®Google Scholar Yates, A.D. (1988) Overlapping functions of the glycosyltransferases encoded by the blood group A and B genes; biochemical basis and practical implications. In: Progress in Immunohaematology, (Ed. by S. B. Moore) p. 65, Arlington, V.A., American Association of Blood Banks. Google Scholar Yates, A.D. & Watkins, W.M. (1982) The biosynthesis of blood group B determinants by the blood group A gene-specified α-3-N-acetylgalactosaminyItransferase. Biochemical and Biophysical Research Communications, 109, 958. 10.1016/0006-291X(82)92033-2 CASPubMedWeb of Science®Google Scholar Yates, A.D., Greenwell, P. & Watkins, W.M. (1984) Overlapping specificities of the glycosyltransferases specified by the blood group A and B genes: a possible explanation for aberrant blood group expression in malignant tissues. Biochemical Society Transactions, 11, 300. 10.1042/bst0110300 Google Scholar Yoshida, A. (1983) The existence of atypical blood group galactosyltransferase which causes an expression of A, in A1B red blood cells. American Journal of Human Genetics, 35, 1117. CASPubMedWeb of Science®Google Scholar Yoshida, A., Yamaguchi, Y.F. & Dave, V. (1979) Immunological homology of human blood group glycosyltransferases and genetic background of blood group (ABO) determinants. Blood, 54, 344. CASPubMedWeb of Science®Google Scholar Yuan, M., Itzkowitz, S. H., Palekar, A. et al.(1986) Distribution of blood group A, B, H, Lewisa and Lewisb in human normal, fetal and malignant colonic tissue. Cancer Research, 45, 4499. PubMedWeb of Science®Google Scholar Citing Literature Volume17, Issue4-5August 1990Pages 259-276 ReferencesRelatedInformation