Fenchylamine Sulfonamide Inhibitors of Amyloid β Peptide Production by the γ-Secretase Proteolytic Pathway: Potential Small-Molecule Therapeutic Agents for the Treatment of Alzheimer's Disease
2000; American Chemical Society; Volume: 43; Issue: 12 Linguagem: Inglês
10.1021/jm990622z
ISSN1520-4804
AutoresGilbert M. Rishton, Daniel M. Retz, Paul Tempest, James Novotny, Steve Kahn, James Treanor, Jack D. Lile, Martin Citron,
Tópico(s)Computational Drug Discovery Methods
ResumoADVERTISEMENT RETURN TO ISSUEPREVLetterNEXTFenchylamine Sulfonamide Inhibitors of Amyloid β Peptide Production by the γ-Secretase Proteolytic Pathway: Potential Small-Molecule Therapeutic Agents for the Treatment of Alzheimer's DiseaseGilbert M. Rishton, Daniel M. Retz, Paul A. Tempest, James Novotny, Steve Kahn, James J. S. Treanor, Jack D. Lile, and Martin CitronView Author Information Amgen, One Amgen Center Drive, Thousand Oaks, California 91320-1789 Cite this: J. Med. Chem. 2000, 43, 12, 2297–2299Publication Date (Web):May 23, 2000Publication History Received21 December 1999Published online23 May 2000Published inissue 1 June 2000https://pubs.acs.org/doi/10.1021/jm990622zhttps://doi.org/10.1021/jm990622zrapid-communicationACS PublicationsCopyright © 2000 American Chemical SocietyRequest reuse permissionsArticle Views807Altmetric-Citations51LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Amines,Inhibition,Inhibitors,Peptides and proteins,Sulfones Get e-Alerts
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