Intravascular Hemolysis in a Patient with Valvular Heart Disease
1966; American College of Physicians; Volume: 65; Issue: 2 Linguagem: Inglês
10.7326/0003-4819-65-2-210
ISSN1539-3704
Autores Tópico(s)Hemoglobinopathies and Related Disorders
ResumoArticle1 August 1966Intravascular Hemolysis in a Patient with Valvular Heart DiseaseDONALD S. MILLER, M.D., CHARLES E. MENGEL, M.D., WILLIAM B. KREMER, M.D., JORDAN GUTTERMAN, M.D., RON SENNINGENDONALD S. MILLER, M.D., CHARLES E. MENGEL, M.D., WILLIAM B. KREMER, M.D., JORDAN GUTTERMAN, M.D., RON SENNINGENAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-65-2-210 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe in vivo role of mechanical factors as a cause of increased destruction of red blood cells has received greater attention recently. This phenomenon was implied by Brain, Dacie, and Hourihane (1) in their studies of patients with bizarre red cells in the setting of small blood vessel disease and the term "microangiopathic hemolytic anemia" was coined. Mechanical factors were also thought to play a role in the hemolysis that has been reported after the implantation of aortic valve prosthesis (2-4). Recently, it has been suggested that damaged, distorted valves, and the accompanying hemodynamic alterations, per se, may cause unusual...References1. BRAINDACIEHOURIHANE MCJVDO: Microangiopathic haemolytic anaemia: the possible role of vascular lesions in the pathogenesis. Brit. J. Haemet. 8: 358, 1962. CrossrefMedlineGoogle Scholar2. STOHLMANSARNOFFCASENESS FSJRBAT: Hemolytic syndrome following the insertion of a lucite ball valve prosthesis into the cardiovascular system. Circulation 13: 586, 1956. CrossrefMedlineGoogle Scholar3. STEVENSONBAKER TDHJ: Hemolytic anemia following insertion of a Starr-Edwards valve prosthesis. Lancet 2: 982, 1964. CrossrefMedlineGoogle Scholar4. MARSH GW: Intravascular hemolytic anemia after aortic valve replacement. Ibid., p. 986. Google Scholar5. 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CrossrefGoogle Scholar18. VERDONFORRESTERCROSBY TARHWH: Hemolytic anemia after open-heart repair of ostium-primum defects. New Eng. J. Med. 269: 444, 1963. CrossrefMedlineGoogle Scholar19. NEILL CA: Postoperative hemolytic anemia in endocardial cushion defects (editorial). Circulation 30: 801, 1964. CrossrefMedlineGoogle Scholar20. SANYLPOLESKYHUMEBROWNE SKHFMMI: Spontaneous partial remission of postoperative hemolytic anemia in a case with ostium-primum defect. Ibid., p. 803. Google Scholar21. DECESARERATHHUFNAGEL WCC: Hemolytic anemia of mechanical origin with aortic-valve prosthesis. New Eng. J. Med. 272: 1045, 1965. CrossrefMedlineGoogle Scholar22. PIROFSKYSUTHERLANDSTARRGRISWOLD BDWAHE: Hemolytic anemia complicating aortic-valve surgery. Ibid., p. 235. Google Scholar23. BRODEURSUTHERLANDKOLERKINSEYGRISWOLD MTDWRDJAHE: Red cell survival in patients with aortic valvular disease and ball valve prosthesis (abstract). Circulation (suppl. 3) 30: 55, 1964. MedlineGoogle Scholar24. MENGELKANNO'MALLEY CEHEBW: Increased hemolysis after intramuscular iron administration in patients with paroxysmal nocturnal hemoglobinuria. Blood 26: 74, 1965. CrossrefMedlineGoogle Scholar25. REYNOLDSCOLTMANROBERTS RDCADK: Sideropenic intravascular hemolysis due to prosthetic valve insufficiency. Clin. Res. 13: 281, 1965. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Durham, North Carolina, and Columbus, OhioFrom the Departments of Medicine, Duke University, Durham, N. C., and The Ohio State University, Columbus, Ohio.This work was supported by grants CA-06452-04 and CA-08170-01, U. S. Public Health Service, Bethesda, Md.Requests for reprints should be addressed to Charles E. Mengel, M.D., Director, Division of Hematology, Ohio State University, 410 W. 10th Ave., Columbus, Ohio 43210. 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Transient, Beneficial Effect of Heparin and Recovery Following Successful Replacement of ValveConfusion Due to Similar LDH Isoenzyme Patterns in Myocardial Infarction and Prosthetic Valve Hemolytic AnemiaIntravascular hemolysis associated with coarctation of the aortaIntracorpuscular Red Cell Defect Masquerading as Valve Induced HemolysisHemolytic Anemia Due to Progressive Enlargement of Silastic Ball Component of Aortic ProsthesisMECHANICAL HEMOLYTIC ANEMIA IN UNOPERATED AORTIC VALVE DISEASESLEEP-RELATED PLASMA HAEMOGLOBIN LEVELS IN PAROXYSMAL NOCTURNAL HAEMOGLOBINURIASerum Lactate Dehydrogenase Elevation in Ambulatory Cardiac PatientsRenal Siderosis Morphology, Etiology, Pathogenesis and Differential Diagnosis 1 August 1966Volume 65, Issue 2Page: 210-215KeywordsBlood vesselsBrainBrain diseasesCardiovascular therapyCellsHemodynamicsHemoglobinHemolytic anemiaMedical servicesRed blood cells Issue Published: 1 August 1966 PDF downloadLoading ...
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