Demyelinating neuropathy in a patient with multiple sclerosis and genotypical HMSN-1
1998; Elsevier BV; Volume: 8; Issue: 2 Linguagem: Inglês
10.1016/s0960-8966(98)00016-9
ISSN1873-2364
AutoresMalaz Almsaddi, Tulio E. Bertorini, William Seltzer,
Tópico(s)Neurological diseases and metabolism
ResumoAbstract Patients with multiple sclerosis (MS) may develop a peripheral neuropathy, sometimes attributed to nutritional deficiency. Other patients present with a demyelinating neuropathy which is presumed to be the result of an autoimmune process that affects both the central and peripheral nervous systems. We report a case of concurring MS and demyelinating neuropathy, without a positive family history, in whom genetic testing proved the neuropathy to be hereditary and not autoimmune. Hereditary neuropathy should be a consideration in sporadic cases of peripheral neuropathy and MS.
Referência(s)