Fast atom bombardment mass spectrometry of insulin, insulin A-chain, insulin B-chain, and glucagon
1984; Wiley; Volume: 11; Issue: 2 Linguagem: Inglês
10.1002/bms.1200110202
ISSN0306-042X
AutoresDominic M. Desiderio, Itsuo Katakuse,
Tópico(s)Ion channel regulation and function
ResumoBiomedical Mass SpectrometryVolume 11, Issue 2 p. 55-59 Article Fast atom bombardment mass spectrometry of insulin, insulin A-chain, insulin B-chain, and glucagon Dominic M. Desiderio, Dominic M. Desiderio Department of Neurology, University of Tennessee Center for Health Sciences, 800 Madison Avenue, Memphis, Tennessee 38163, USA Charles B. Stout Neuroscience Mass Spectrometry Laboratory, University of Tennessee Center for Health Sciences, 800 Madison Avenue, Memphis, Tennessee 38163, USASearch for more papers by this authorItsuo Katakuse, Itsuo Katakuse Department of Neurology, University of Tennessee Center for Health Sciences, 800 Madison Avenue, Memphis, Tennessee 38163, USA Charles B. Stout Neuroscience Mass Spectrometry Laboratory, University of Tennessee Center for Health Sciences, 800 Madison Avenue, Memphis, Tennessee 38163, USA On leave from the Department of Physics, Faculty of Science, Osaka University, Osaka, Japan.Search for more papers by this author Dominic M. Desiderio, Dominic M. Desiderio Department of Neurology, University of Tennessee Center for Health Sciences, 800 Madison Avenue, Memphis, Tennessee 38163, USA Charles B. Stout Neuroscience Mass Spectrometry Laboratory, University of Tennessee Center for Health Sciences, 800 Madison Avenue, Memphis, Tennessee 38163, USASearch for more papers by this authorItsuo Katakuse, Itsuo Katakuse Department of Neurology, University of Tennessee Center for Health Sciences, 800 Madison Avenue, Memphis, Tennessee 38163, USA Charles B. Stout Neuroscience Mass Spectrometry Laboratory, University of Tennessee Center for Health Sciences, 800 Madison Avenue, Memphis, Tennessee 38163, USA On leave from the Department of Physics, Faculty of Science, Osaka University, Osaka, Japan.Search for more papers by this author First published: February 1984 https://doi.org/10.1002/bms.1200110202Citations: 21 AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Abstract Fast atom bombardment mass spectral data are presented for the polypeptides insulin, oxidized insulin A-chain, carboxymethylated insulin B-chain, and glucagon. The doubly-charged molecular ion of the intact insulin molecule produced with fast atom bombardment with xenon atoms is observed at a reduced accelerating voltage (4 kV). References 1 M. Barber, R. S. Bordoli, R. D. Sedgwick, A. N. Tyler, G. V. Garner, D. B. Gordon, L. W. Tetler and R. C. Hider, Biomed. Mass Spectrom. 9, 265 (1982). 2 M. Barber, R. S. Bordoli, R. D. Sedgwick and A. N. Tyler, Biomed. Mass Spectrom. 9, 208 (1982). 3 M. Barber, R. S. Bordoli, R. D. Sedgwick, A. N. Tyler and E. T. Whalley, Biomed. Mass Spectrom. 8, 337 (1981). 4 M. Barber, R. S. Bordoli, G. V. Garner, D. B. Gordon, T. D. Sedgwick, L. W. Tetler and A. N. Tyler, Biochem. J. 197, 401 (1981). 5 M. Barber, R. S. Bordoli, G. J. Elliott, R. D. Sedgwick, A. N. 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Citing Literature Volume11, Issue2February 1984Pages 55-59 ReferencesRelatedInformation
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