Artigo Revisado por pares

A Highly Practical Instant Catalyst for Cyclotrimerization of Alkynes to Substituted Benzenes

2006; American Chemical Society; Volume: 8; Issue: 7 Linguagem: Inglês

10.1021/ol0602295

ISSN

1523-7060

Autores

Naoko Saino, Fumihiro Amemiya, Emi Tanabe, Kouki Kase, Sentaro Okamoto,

Tópico(s)

Catalytic C–H Functionalization Methods

Resumo

[reaction: see text] A 2-(2,6-diisopropylphenyl)iminomethylpyridine (1a)/CoCl(2).6H(2)O/Zn reagent has been developed as an effective instant catalyst for the intra- and intermolecular cyclotrimerization of alkynes to substituted benzenes, making the method extremely practical since the reagent, 1a/CoCl(2).6H(2)O/Zn, is inexpensive and easy to handle and the reaction is less sensitive to moisture and is reasonably general.

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