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Using fluorescence in situ hybridization (FISH) in genome mapping

1992; Elsevier BV; Volume: 10; Linguagem: Inglês

10.1016/0167-7799(92)90163-p

0167-9430

Julie R. Korenberg, Teresa L. Yang‐Feng, Rhona Schreck, Xiao-Ning Chen,

Genomics and Phylogenetic Studies

Fluorescence in situ hybridization (FISH) provides one of the most effective and rapid approaches for assigning and ordering DNA fragments within single eukaryotic chromosome bands. These techniques have wide applications not only for the mapping of the human genome and the genomes of other organisms, but also in clinical cytogenetics, somatic cell genetics, cancer diagnosis and gene expression studies1–4.