Edinger-Westphal nucleus: Cells that project to spinal cord contain corticotropin-releasing factor
1987; Elsevier BV; Volume: 83; Issue: 1-2 Linguagem: Inglês
10.1016/0304-3940(87)90208-4
ISSN1872-7972
AutoresRichard Y. Chung, Peggy Mason, Andrew M. Strassman, R. Maciewicz,
Tópico(s)Neuroendocrine regulation and behavior
ResumoCombined retrograde transport and immunocytochemical methods were used to determine whether neurons in the Edinger-Westphal complex (EW) that project to the spinal cord also demonstrate corticotropin-releasing factor-like immunoreactivity (CRF-LI). Large injections of horseradish peroxidase (HRP) into cervical spinal cord retrogradely labeled cells throughout the extent of the EW complex. Most retrogradely labeled EW neurons also exhibited CRF-LI, evidence that EW is the origin of a direct CRF-containing pathway which links the rostral mesencephalon with spinal cord.
Referência(s)