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BIBTEX RIS

An Enzyme-Labile Safety Catch Linker for Combinatorial Synthesis on a Soluble Polymeric Support

2000; Wiley; Volume: 39; Issue: 9 Linguagem: Inglês

10.1002/(sici)1521-3773(20000502)39

ISSN

1521-3773

Autores

Uwe Grether, Herbert Waldmann,

Tópico(s)

Click Chemistry and Applications

Resumo

An enzyme-initiated cyclization allows the release of different target molecules from a soluble polymeric support (see picture) under mild conditions (pH 7, 37 °C) and in high yield. X = O, NH, NR.

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