Methanesulfonic Acid/SiO 2 as an Efficient Combination for the Synthesis of 2-Substituted Aromatic and Aliphatic Benzothiazoles from Carboxylic Acids
2009; Taylor & Francis; Volume: 39; Issue: 5 Linguagem: Inglês
10.1080/00397910802431214
ISSN1532-2432
Autores Tópico(s)Synthesis and biological activity
ResumoAbstract Methanesulfonic acid/SiO2 (1 mL/0.3 g) was found to be as an expeditious mixture in the synthesis of 2-substituted aromatic and aliphatic benzothiazoles at 140 °C using carboxylic acids. After a simple workup, benzothiazoles were obtained in good yields. Simplicity, use of widely available and diverse carboxylic acids, and easy handling of the reaction conditions are among the benefits of the method.
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