Cardiac Abnormalities in Poisoning with Tricyclic Antidepressants
1969; BMJ; Volume: 2; Issue: 5657 Linguagem: Inglês
10.1136/bmj.2.5657.610
ISSN0959-8138
AutoresJames W. Freeman, G. R. Mundy, R. R. Beattie, Conor Ryan,
Tópico(s)Plant-based Medicinal Research
ResumoOf 80 consecutive admissions to a general hospital for drug overdose, 10 had taken one or other of the tricyclic antidepressants. All 10 had abnormalities of cardiac conduction as shown by prolonged Q–T e intervals, and eight had S–T segment and T-wave changes. Five of the 10 patients had arrhythmias and two of these died. Continuous electrocardiographic monitoring is recommended in patients with overdosage of tricyclic antidepressants.
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