Amino acid metabolism in liver disease
1999; Lippincott Williams & Wilkins; Volume: 2; Issue: 1 Linguagem: Inglês
10.1097/00075197-199901000-00009
ISSN1473-6519
AutoresE. Holm, Oliver Sedlaczek, Eva Grips,
Tópico(s)Alcoholism and Thiamine Deficiency
ResumoThe impairment of transsulphuration during methionine degradation in hepatic failure can be counteracted by treatment with S-adenosylmethionine. Regarding the pathogenesis of hepatic encephalopathy, no convincing evidence exists for tryptophan, glutamine or glutamate being involved. Portal-systemic shunting-induced hyperammonaemia may reduce plasma branched-chain amino acids. The glucose effect on urea synthesis does not exist in cirrhosis.
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