Long-Term Mortality Rates in Acute De Novo Versus Acute-on-Chronic Heart Failure
2014; SAGE Publishing; Volume: 66; Issue: 9 Linguagem: Inglês
10.1177/0003319714563138
ISSN1940-1574
AutoresKhalid F. AlHabib, Tarek Kashour, Abdelfatah Elasfar, Hussam AlFaleh, Ahmad Hersi, Mostafa Q. Alshamiri, Fayez Alshaer, Layth Mimish, Ali Almasood, Waleed AlHabeeb, Saleh Alghamdi, Abdullah Ghabashi, KaziNur Asfina, Hani Altaradi, Omar Alnobani, Nour Alkamel, Lukman Thalib,
Tópico(s)Mechanical Circulatory Support Devices
ResumoAim: The heart function assessment registry trial in Saudi Arabia (HEARTS) is a national multicenter project that compared de novo versus acute-on-chronic heart failure (ACHF). Methods and Results: This is a prospective registry in 18 hospitals in Saudi Arabia between October 2009 and December 2010. The study enrolled 2610 patients: 940 (36%) de novo and 1670 (64%) ACHF. Patients with ACHF were significantly older (62.2 vs 60 years), less likely to be males (64% vs 69%) or smokers (31.6% vs 36.7%), and more likely to have history of diabetes mellitus (65.7% vs 61.3%), hypertension (74% vs 65%), and severe left ventricular dysfunction (52% vs 40%). The ACHF group had a higher adjusted 3-year mortality rate (hazard ratio, 1.6; 95% confidence interval [CI] 1.3-2.0; P < .001). Conclusion: Patients with ACHF had significantly higher long-term mortality rates than those with de novo acute heart failure (HF). Multidisciplinary HF disease management programs are highly needed for such high-risk populations.
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