30 mm regeneration of rat sciatic nerve along collagen filaments
2002; Elsevier BV; Volume: 949; Issue: 1-2 Linguagem: Inglês
10.1016/s0006-8993(02)03149-9
ISSN1872-6240
AutoresSatoru Yoshii, Masanori Oka, Mitsuhiro Shima, Ataru Taniguchi, Masao Akagi,
Tópico(s)Electrospun Nanofibers in Biomedical Applications
ResumoThis paper describes 30 mm regeneration of peripheral nerve axons along collagen filaments; 31-mm-long collagen filaments or collagen tube were grafted to bridge a 30-mm defect of rat sciatic nerve. The mean number and the diameter of regenerated myelinated axons were 330±227 and 2.7±0.9 μm at the distal end of the collagen-filaments 12 weeks postoperatively; while at the distal end of the tube no axon was found.
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