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One Micrometer Resolution NMR Microscopy

2001; Elsevier BV; Volume: 150; Issue: 2 Linguagem: Inglês

10.1006/jmre.2001.2319

1096-0856

Seung‐Cheol Lee, Kiseong Kim, Jung-Hyun Kim, Soonchil Lee, Jeong Han Yi, Sung Woo Kim, Kwon‐Soo Ha, Chaejoon Cheong,

Advanced NMR Techniques and Applications

We obtained a magnetic resonance image of 1μm resolution and 75μm3 voxel volume for a phantom filled with hydrocarbon oil within an hour at 14.1 T. For this work, a specially designed probe with a high sensitivity RF coil and gradient coils generating over 1000 G/cm was built. The optimal pulse sequence was analyzed in consideration of the bandwidth, diffusion coefficients, and T1 and T2 relaxations of the medium. The system was applied to the in vivo imaging of a geranium leaf stem to get the images of 2μm resolution and 200μm3 voxel volume.