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Ultrasound Guided Seminal Vesicle Biopsies in Men with Suspected Prostate Cancer

1995; Lippincott Williams & Wilkins; Volume: 154; Issue: 5 Linguagem: Inglês

10.1016/s0022-5347(01)66787-9

1527-3792

Prabhakar Pandey, Jackson E. Fowler, Linda E. Seaver, Tony P. Peliz, Jay P. Brooks,

Genital Health and Disease

No AccessJournal of UrologyClinical Urology: Original Article1 Nov 1995Ultrasound Guided Seminal Vesicle Biopsies in Men with Suspected Prostate Cancer Prabhakar Pandey, Jackson E. Fowler, Linda E. Seaver, Tony P. Peliz, and Jay P. Brooks Prabhakar PandeyPrabhakar Pandey , Jackson E. FowlerJackson E. Fowler , Linda E. SeaverLinda E. Seaver , Tony P. PelizTony P. Peliz , and Jay P. BrooksJay P. Brooks View All Author Informationhttps://doi.org/10.1016/S0022-5347(01)66787-9AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: The histology of ultrasound guided seminal vesicle biopsies is assessed and the results are correlated with clinical or pathological stage of prostate cancer. Materials and Methods: A total of 517 consecutive men underwent bilateral (515) or unilateral (2) seminal vesicle biopsy during sextant biopsy of the prostate. Results: Seminal vesicle epithelium and muscularis were identified in 490 or 1,032 biopsy specimens (47 percent) and smooth muscle consistent with seminal vesicle muscularis was identified in 393 (38 percent). The seminal vesicle biopsy was positive for cancer in 7 of 123 patients (6 percent) with clinical stages T1c and T2 tumors, 27 of 60 (45 percent) with stages T3 to 4 disease and 9 of 13 (69 percent) with metastatic cancer. Of 39 patients who underwent radical prostatectomy 1 of 36 (3 percent) without and 0 of 3 (0 percent) with seminal vesicle invasion had a positive seminal vesicle biopsy. Conclusions: Seminal vesicle epithelium and muscularis or smooth muscle consistent with the seminal vesicle muscularis can be procured in most patients using contemporary ultrasound guided biopsy techniques. However, apparently false-negative seminal vesicle biopsies are not uncommon and seminal vesicle biopsies contribute little to the staging of T1c and T2 tumors. References 1 : Serum PSA after anatomic radical prostatectomy. The Johns Hopkins experience after 10 years. Urol. Clin. N. Amer.1993; 20: 713. Google Scholar 2 : The mechanisms and prognostic significance of seminal vesicle involvement by prostate cancer. Amer. J. Surg. Path.1993; 17: 1252. Google Scholar 3 : Pathogenesis and biological significance of seminal vesicle invasion in prostatic adenocarcinoma. J. Urol.1990; 143: 1183. Link, Google Scholar 4 : Correlation of pathologic findings with progression after radical retropubic prostatectomy. Cancer1993; 71: 3582. Crossref, Medline, Google Scholar 5 : Efficacy of transrectal ultrasound-guided seminal vesicle biopsies in the detection of seminal vesicle invasion by prostate cancer. J. Urol.1993; 149: 1035. Link, Google Scholar 6 : Influence of preoperative positive seminal vesicle biopsy on the staging of prostatic cancer. J. Urol.1994; 152: 1152. Abstract, Google Scholar 7 : The TNM classification of prostate cancer. Prostate1992; 4: 129. Crossref, Google Scholar 8 : Random systematic versus directed ultrasound guided transrectal core biopsies of the prostate. J. Urol.1989; 142: 71. Link, Google Scholar 9 : Invasion of the seminal vesicles by prostatic cancer: detection with transrectal sonography. AJR1990; 155: 811. Google Scholar 10 : Prostatic evaluation by transrectal endosonography: detection of carcinoma. Radiology1986; 158: 85. Google Scholar 11 : Variable histology of anastomotic biopsies with detectable prostate specific antigen after radical prostatectomy. J. Urol.1995; 153: 1011. Link, Google Scholar 12 : Indications for seminal vesicle biopsy and laparoscopic pelvic lymph node dissection in men with localized carcinoma of the prostate. J. Urol.1995; 153: 429A. abstract 802. Google Scholar Division of Urology and Department of Pathology, University of Mississippi Medical Center, Jackson, Mississippi.© 1995 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited byGuzzo T, Vira M, Wang Y, Tomaszewski J, D'amico A, Wein A and Malkowicz S (2018) Preoperative Parameters, Including Percent Positive Biopsy, in Predicting Seminal Vesicle Involvement in Patients with Prostate CancerJournal of Urology, VOL. 175, NO. 2, (518-522), Online publication date: 1-Feb-2006.KOH H, KATTAN M, SCARDINO P, SUYAMA K, MARU N, SLAWIN K, WHEELER T and OHORI M (2018) A Nomogram to Predict Seminal Vesicle Invasion by the Extent and Location of Cancer in Systematic Biopsy ResultsJournal of Urology, VOL. 170, NO. 4 Part 1, (1203-1208), Online publication date: 1-Oct-2003. Volume 154Issue 5November 1995Page: 1798-1801 Advertisement Copyright & Permissions© 1995 by American Urological Association, Inc.Metrics Author Information Prabhakar Pandey More articles by this author Jackson E. Fowler More articles by this author Linda E. Seaver More articles by this author Tony P. Peliz More articles by this author Jay P. Brooks More articles by this author Expand All Advertisement PDF downloadLoading ...