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Oxytalan Fibers in Fuchs' Endothelial Dystrophy

1981; American Medical Association; Volume: 99; Issue: 9 Linguagem: Inglês

10.1001/archopht.1981.03930020496021

1538-3601

Robert Alexander, Ian Grierson, A Garner,

Protease and Inhibitor Mechanisms

• In a histochemical and electron microscopic study of nine cases of Fuchs' endothelial dystrophy, oxytalan, a component of the elastic fiber family, was found in the extracellular tissues of the cornea. Oxytalan was most abundant around but not within the guttate excrescences; it was also found beneath the epithelium, occasionally beneath Bowman's layer, and rarely deep within the stroma.