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The constituents of Schizandra chinensis Baill. XV. Isolation and structure determination of two new lignans, gomisin S and gomisin T.

1988; Pharmaceutical Society of Japan; Volume: 36; Issue: 10 Linguagem: Inglês

10.1248/cpb.36.3974

1347-5223

Yukinobu Ikeya, Hirotoshi Kanatani, Hakozaki Misako, HEIHACHIRO TAGUCHI, Hiroshi Mitsuhashi,

Phytochemistry and Biological Activities

Two new dibenzocyclooctadiene lignans, gomisin S (1) and gomisin T (2), were isolated from the fruits of Schizandra chinensis BAILL.(Schizandraceae). On the basis of spectral methods and chemical transformations, the structures of 1 and 2 were elucidated as (6S, 7S, 8S, S-biar)-5, 6, 7, 8-tetrahydro-1, 2, 10, 11, 12-pentamethoxy-6, 7-dimethy1-3, 8-dibenzo [a, c] cyclooctenediol and (6S, 7S, R-biar)-5, 6, 7, 8-tetrahydro-1, 2, 10, 11, 12-pentamethoxy-6, 7-dimethy1-3, 7-dibenzo [a, c] cyclooctenediol, respectively.