Triterpenoids from the leaves of Psidium guajava
2002; Elsevier BV; Volume: 61; Issue: 4 Linguagem: Inglês
10.1016/s0031-9422(02)00190-5
ISSN1873-3700
AutoresSabira Begum, Syed Imran Hassan, Bina S. Siddiqui, Farzana Shaheen, Muhammad Nabeel Ghayur, Anwarul Hassan Gilani,
Tópico(s)Phytochemistry Medicinal Plant Applications
ResumoTwo triterpenoids, 20beta-acetoxy-2alpha,3beta-dihydroxyurs-12-en-28-oic acid (guavanoic acid, 3), and 2alpha,3beta-dihydroxy-24-p-z-coumaroyloxyurs-12-en-28-oic acid (guavacoumaric acid, 7), along with six known compounds 2alpha-hydroxyursolic acid (1), jacoumaric acid (2), isoneriucoumaric acid (4), asiatic acid (5), ilelatifol D (6) and beta-sitosterol-3-O-beta-D-glucopyranoside (8), have been isolated from the leaves of Psidium guajava. Their structures were determined through spectroscopic methods. Compound 5 showed dose-dependent (10-500 microg/ml) spasmolytic activity in spontaneously contracting isolated rabbit jejunum preparations.
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