Role of Magnesium in Cardiovascular Diseases
2014; Lippincott Williams & Wilkins; Volume: 22; Issue: 4 Linguagem: Inglês
10.1097/crd.0000000000000003
ISSN1538-4683
AutoresDhaval Kolte, Krishnaswami Vijayaraghavan, Sahil Khera, Domenic A. Sica, William H. Frishman,
Tópico(s)Apelin-related biomedical research
ResumoMagnesium, the fourth most abundant cation in the human body, is involved in several essential physiological, biochemical, and cellular processes regulating cardiovascular function. It plays a critical role in modulating vascular smooth muscle tone, endothelial cell function, and myocardial excitability and is thus central to the pathogenesis of several cardiovascular disorders such as hypertension, atherosclerosis, coronary artery disease, congestive heart failure, and cardiac arrhythmias. This review discusses the vasodilatory, anti-inflammatory, anti-ischemic, and antiarrhythmic properties of magnesium and its current role in the prevention and treatment of cardiovascular disorders.
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