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Colorectal cancer, screening and survival: the influence of socio-economic deprivation

2003; Elsevier BV; Volume: 117; Issue: 6 Linguagem: Inglês

10.1016/s0033-3506(03)00146-x

1476-5616

D K Whynes, Emma Frew, C.M Manghan, J H Scholefield, J D Hardcastle,

Diverticular Disease and Complications

Objectives. To determine the extent to which socio-economic deprivation explains colorectal cancer prevalence, subject participation in screening, and postoperative survival and life expectancy. Methods. Regression analyses of clinical data from a large randomized controlled trial, augmented by geographical-based indices of deprivation. Results. Deprivation appears to exert no significant impact on colorectal cancer prevalence but is a major factor explaining subject participation in screening. Cancer detection at later stages reduces life expectancy at time of treatment. Females from more-deprived areas have poorer post-treatment life expectancies and survival prospects, independently of their screening behaviour. Conclusions. Screening increases the chances of having a cancer treated at an earlier stage, and treatment at an earlier stage is associated with longer subsequent life expectancy. However, those from more-deprived areas are less likely to accept an invitation to be screened.