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MECHANISM OF BACITRACIN ACTION: A SPECIFIC LIPID‐PEPTIDE INTERACTION*

1974; Wiley; Volume: 235; Issue: 1 Linguagem: Inglês

10.1111/j.1749-6632.1974.tb43278.x

1749-6632

Daniel R. Storm,

Antibiotics Pharmacokinetics and Efficacy

Annals of the New York Academy of SciencesVolume 235, Issue 1 p. 387-398 MECHANISM OF BACITRACIN ACTION: A SPECIFIC LIPID-PEPTIDE INTERACTION* Daniel R. Storm, Daniel R. Storm The Biological Laboratories Harvard University Cambridge, Massachusetts 02138 Recipient of a National Science Foundation Postdoctoral Fellowship.Present address: Department of Biochemistry, School of Chemical Sciences, University of Illinois, Urbana, Ill. 61801.Search for more papers by this author Daniel R. Storm, Daniel R. Storm The Biological Laboratories Harvard University Cambridge, Massachusetts 02138 Recipient of a National Science Foundation Postdoctoral Fellowship.Present address: Department of Biochemistry, School of Chemical Sciences, University of Illinois, Urbana, Ill. 61801.Search for more papers by this author First published: May 1974 https://doi.org/10.1111/j.1749-6632.1974.tb43278.xCitations: 64 * Supported by Research Grant AM-13230 from the United States Public Health Service. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1 Adler, R. H. & J. E. Snoke. 1961. Requirement of divalent metal ions for bacitracin activity. J. Bacteriol. 83: 1315. 2 Garbutt, J. T., A. L. Morehouse & A. M. Hanson. 1961. Metal binding properties of bacitracin. Agr. Food Chem. 9: 285. 3 Hummel, J. P. & W. J. Dreyer. 1962. Measurement of protein-binding phenomena by gel filtration. Biochim. Biophys. Acta 63: 530. 4 Johnson, B. A., H. Anker & F. L. Meleney. 1945. Bacitracin: a new antibiotic produced by a member of the B. subtilis group. Science 102: 376. 5 Konigsberg, W. & L. C. Craig. 1959. Cellulose ion exchange and rotary dispersion studies with the bacitracin polypeptides. J. Amer. Chem. Soc. 81: 3452. 6 Siewert, G. & I. L. Strominger. 1967. Bacitracin: an inhibitor of the dephosphorylation of lipid pyrophosphate, an intermediate in biosynthesis of the peptidoglycan of bacterial cell walls. Proc. Nat. Acad. Sci. USA 57: 767. 7 Stone, K. J. & J. L. Strominger. 1971. Mechanism of action of bacitracin: complexation with metal ion and C55-isoprenyl pyrophosphate. Proc. Nat. Acad. Sci. USA 68: 3223. 8 Stone, K. J. & J. L. Strominger. 1972. Preparation of C55-isoprenyl pyrophosphate. Methods Enzymol. XXVII: 306. 9 Storm, D. R. & J. L. Strominger. 1973a. Complex formation between bacitracin peptides and isoprenyl pyrophosphate. J. Biol. Chem. 248: 5208. 10 Storm, D. R. & J. L. Strominger. 1973b. Binding of [3H]Bacitracin to Micrococcus lysodeikticus. In preparation. 11 Weinberg, E. D. 1967. In Bacitracin in Antibiotics: Mechanism of Action. I. D. Gottlieb & P. Shaw, Eds.: 90. 12 Hancock, R. & P. C. Fitz-James. 1964. J. Bacteriol. 87: 1044. 13 Reynolds, P. E. 1971. Biochim. Biophys. Acta 237: 255. Citing Literature Volume235, Issue1Mode of Action of Antibiotics on Microbial Walls and MembranesMay 1974Pages 387-398 ReferencesRelatedInformation