Portal de Periódicos da CAPES

An Historical Account of the Study of Progressive Systemic Sclerosis (Diffuse Scleroderma)

1962; American College of Physicians; Volume: 57; Issue: 2_Part_1 Linguagem: Inglês

10.7326/0003-4819-57-2-305

1539-3704

Gerald P. Rodnan,

Hypertrophic osteoarthropathy and related conditions

Medical History1 August 1962An Historical Account of the Study of Progressive Systemic Sclerosis (Diffuse Scleroderma)GERALD P. RODNAN, M.D., THOMAS G. BENEDEK, M.D.GERALD P. RODNAN, M.D., THOMAS G. BENEDEK, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-57-2-305 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptRien n'est plus bizarre, mais aussi rien n'est plus intéressant que la dégénération cornée du systême dermoïde. Elle sera toujours pour les médecins un grand sujet d'étude et de méditation, tant qu' ils ajouteront quelque prix aux recherches physiologiques.—Alibert, 1818 (1)Progressive systemic sclerosis (diffuse scleroderma) is now recognized to be a widespread disturbance of connective tissue with characteristic involvement of the skin (scleroderma), synovium, and various internal organs, particularly the heart, lung, gastrointestinal tract, and kidney (2-12). The present paper is concerned with both the rather long history of scleroderma and with the recognition of the systemic nature...References NOTE1. ALIBERT JL: Précis Théorique et Pratique sur les Maladies de la Peau, vol. 2, Caille & Ravier, Paris, 1818, pp. 168-170. Google Scholar*2. GOETZ RH: Pathology of progressive systemic sclerosis (generalized scleroderma) with special reference to changes in the viscera. Clin. Proc. (S. Afr.) 4: 337, 1945. Google Scholar3. LEINWANDDURYEERICHTER IAWMN: Scleroderma (based on a study of over 150 cases). Ann. Intern. Med. 41: 1003, 1954. LinkGoogle Scholar4. OPIE LH: Pulmonary manifestations of generalized scleroderma (progressive systemic sclerosis). Dis. Chest 28: 665, 1955. CrossrefMedlineGoogle Scholar5. PIPERHELLWIG WNEB: Progressive systemic sclerosis: visceral manifestations in generalized scleroderma. Arch. Derm. Syph. 72: 535, 1955. Google Scholar6. TALBOTTFERRANDIS JHRM: Collagen Diseases, Grune & Stratton, Inc., New York, 1956, p. 137. Google Scholar7. GOLDGRABERKIRSNER MBJB: Scleroderma of the gastrointestinal tract. Arch. Path. 64: 255, 1957. MedlineGoogle Scholar8. ORABONAALBANO MLO: Systemic progressive sclerosis (or visceral scleroderma). Review of the literature and report of cases. Acta Med. Scand. 160: supp. 333, 1957. Google Scholar9. RODNANSCHREINERBLACK GPGERL: Renal involvement in progressive systemic sclerosis (generalized scleroderma). Amer. J. Med. 23: 445, 1957. CrossrefMedlineGoogle Scholar10. GONDOS B: Roentgen manifestations in progressive systemic sclerosis ( diffuse scleroderma). Amer. J. Roentgenol. 84: 235, 1960. Google Scholar11. RODNANYUNISTOTTEN GPERS: (a) Experience with punch biopsy of synovium in study of joint disease. Ann. Intern. Med. 53: 319, 1960; (b) The nature of joint involvement in progressive systemic sclerosis (diffuse scleroderma). Clinical study and pathologic examination of synovium in 29 patients. Ann. Intern. Med. 56: 422, 1962. LinkGoogle Scholar12. TUFFANELLIWINKLEMANN DLRK: Systemic scleroderma. A clinical study of 727 cases. Arch. Derm. 84: 359, 1961. CrossrefMedlineGoogle Scholar*13. WOLTERS M: Beitrag zur Kenntniss der Sclerodermie. Arch. Derm. Syph. 24: 695, 943, 1892. CrossrefGoogle Scholar14. GALEN : Causes and treatment of constriction of the pores, in A Translation of Galen's Hygiene (De Sanitate Tuenda), ed. by Green, R. M., Charles C Thomas, Springfield, Illinois, 1951, p. 131. CrossrefGoogle Scholar15. DE DIEMERBROECK I: in Opera Omnia, Anatomica et Medica, Vol. 8, (de Nervis) ed. by de Diemerbroeck, T., Meinardum à Dreunen and Guilielmum à Walchern, 1685, p. 502. Google Scholar16. MACHIN J: An extract from the minutes of the Royal Society, March 16, 1731, containing an uncommon case of a distempered skin. Philos. Trans. Roy. Soc. Lond. 37: 299, 1731. CrossrefGoogle Scholar17. VATER A: A singular cutaneous affection. Philos. Trans. Roy. Soc. Lond. (abridged) 8: 59, 1809. Google Scholar*18 CURZIO C: (a) Discussioni Anatomico-Pratiche di un raro, e stravagante morbo cutaneo in una giovane Donna felicemente curato in questo grande Ospedale degl' Incurabili, Giovanni di Simone, Napoli, 1753; (b) Dissertation Anatomique et Pratique sur une Maladie de la Peau, d'une espece fort rare & fort singuliere, translated by Vandermonde, Vincent, Paris, 1755. Google Scholar19. WATSON R: An account of an extraordinary disease of the skin, and its cure. Extracted from the Italian of Carlo Crusio; accompanied with a letter of the Abbé Nollet, F.R.S., to Mr. William Watson, F.R.S. Philos. Trans. Roy. Soc. Lond. 48: 579, 1754. Google Scholar20. WILLAN R: On Cutaneous Diseases, vol. 1, J. Johnson, London, 1808, p. 207. Google Scholar21. BATEMAN T: A Practical Synopsis of Cutaneous Diseases, According to the Arrangement of Dr. Willan, 2d American ed., James Crissy, Philadelphia, 1824, p. 51. Google Scholar22. ALIBERT JL: Nosologie Naturelle ou Les Maladies du Corps Human Distribuées par Familles, Vol. 1, Caille & Ravier, Paris, 1817, p. 494. Google Scholar23. GRISOLLE M: Cas rare de maladie de la peau. Gaz. Hôp. Civ. Milit. (Paris) 9: 209, 1847. Google Scholar24. FORGET C: Mémoire sur le chorionitis ou la sclérosténose cutanée (maladie non décrite par les auteurs). Gaz. Méd. Strasbourg 7: 200, 1847. Google Scholar25. THIRIAL H (a) Du sclérème chez les adultes, comparé au sclérème chez les nouveau-nés. Du parallèle entre ces deux formes diverses de la maladie, comme moyen d'en éclairer la nature. J. Méd. (Paris) 3: 137, 161, 1845; (b) De sclérème des adultes. Identité de cette maladie et de celle que M. Forget, de Strasbourg, vient de présenter comme nouvelle sous le nom de chorionitis. -Discussion sur la nature de cette affection singulière. Union Méd. 1: 422, 430, 1847. Google Scholar*26. GINTRAC E: Note sur la sclérodermie. Rev. Méd. Chir. (Paris) 2: 263, 1847. Google Scholar*27. HORTELOUP P: De la Sclérodermie, P. Asselin, Paris, 1865. Google Scholar*28. KAPOSI M: Scleroderma adultorum, in On Diseases of the Skin, Including the Exanthemata, vol. 3, by Hebra, F., and Kaposi, M., translated by Tay, W., The New Sydenham Society, London, 1874, p. 104. Google Scholar*29. LEWINHELLER GJ: Die Sclerodermie, A. Hirschwald, Berlin, 1895. Google Scholar30. ARNOLD AB: Three cases of scleroderma; with remarks. Amer. J. Med. Sci. 58: 89, 1869. CrossrefGoogle Scholar31. DAY WD: Case of scleroderma or sclerema, with the autopsy and remarks. Amer. J. Med. Sci. 59: 350, 1870. CrossrefGoogle Scholar*32. ATKINSONWEBER FRFP: Cutaneous and subcutaneous calcinosis. Brit. J. Derm. Syph. 50: 267, 1938. CrossrefGoogle Scholar33. WEBER H: Case presentation. Correspondentzblatt Schweiz. Aerzte (Basel) 8: 623, 1878. Google Scholar34. THIBIERGEWEISSENBACH GR: (a) Une forme de concrétions calcaire sous-cutanées en relation avec la sclérodermie. Bull. Mém. Soc. Méd. Hôp. Paris 30: 10, 1910; (b) Concrétions calcaire sous-cutanées et sclérodermie. Ann. Derm. Syph. 2: 129, 1911. Google Scholar35. SCHOLEFIELDWEBER REFP: A case of sclerodactylia with subcutaneous calcareous concretions. Brit. J. Derm. 23: 276, 1911. CrossrefGoogle Scholar36. BROOKS WD: Calcinosis. Quart. J. Med. 3: 293, 1934. Google Scholar37. FOX TC: Note on the history of sclerodermia in England. Brit. J. Derm. 4: 101, 1892. Google Scholar*38. ADDISON T: On the keloid of Alibert and on true keloid. Med. Chir. Trans. 19: 27, 1854. CrossrefGoogle Scholar39. MOYNAHAN EJ: Addison's place in dermatology. Guy. Hosp. Rep. 109: 262, 1960. Google Scholar*40. FAGGE CH: On keloid, scleriasis, morphoea and some allied affections. Guy. Hosp. Rep 13: 255, 1868. Google Scholar41. WILSON E: (a) On Diseases of the Skin 4th American ed. from the 4th English ed., Blanchard and Lea, Philadelphia, 1857, p. 341; (b) On striae et maculae atrophicae cutis or false cicatrices of the skin. J. Cutan. Med. Dis. Skin 1: 140, 1868; (c) Morphoea. J. Cutan. Med. Dis. Skin 2: 430, 1869. Google Scholar42. DOYLE AC: The adventure of the blanched soldier, in The Complete Sherlock Holmes, Garden City Publishing Company, Garden City, New York, n.d., p. 1179. Google Scholar43. CROCKER HR: Diseases of the skin. 1. The histology and pathology of morphoea and its relation to scleroderma adultorum. Trans. Path. Soc. Lond. 31: 315, 1880. Google Scholar44. DUCKWORTH D: A case of scleroderma adultorum, illustrating the circumscribed and the diffuse forms of the malady. Trans. Path. Soc. Lond. 31: 322, 1880. Google Scholar45. CROCKER HR: Clinical notes on scleroderma. Lecture II. Circumscribed and mixed scleroderma. Lancet 1: 975, 1885. Google Scholar46. HUTCHINSON J: Report on morphoea and sclerodermia. Nos. XVIII and XXV. Arch. Surg. 3: 30, 40, 1892. Google Scholar47. DUHRING LA: A Practical Treatise on Diseases of the Skin, 2d ed., J. B. Lippincott Company, Philadelphia, 1881, p. 369. Google Scholar*48. RAYNAUD M: (a) On Local Asphyxia and Symmetrical Gangrene of the Extremities. (De L'asphyxie Locale et de la Gangrène Symétrique des Extrémites, 1862), translated by Barlow, T., The New Sydenham Society, London, 1888; (b) New Researches on the Nature and Treament of Local Asphyxia of the Extremities, (Nouvelles Recherches sur la Nature et le Traitement de l'Asphyxie Locale des Extrémités 1874) translated by Barlow, T., The New Sydenham Society, London, 1888. Google Scholar49. PUTÉGNAT E: Sur le chorionitis ou scléroténose de la peau. J. Méd. Chir. Pharm. (Bruxelles) 5: 789, 1847. Google Scholar50. RAYNAUD M: Gangrène symétrique des extrémités, in Nouveau Dictionnaire de Médecine et de Chirurgie Pratiques, vol. 15, J. B. Baillière et Fils, Paris, 1872, p. 636. Google Scholar51. BARLOW T: Appendix by the translator, in On Local Asphyxia and Symmetrical Gangrene of the Extremities, The New Sydenham Society, London, 1888, p. 189. Google Scholar52. MONRO TK: Raynaud's Disease. (Local Syncope, Local Asphyxia, Symmetrical Gangrene). Its History, Causes, Symptoms, Morbid Relations, Pathology, & Treatment, J. Maclehose & Sons, Glasgow, 1899, p. 163. Google Scholar53. HUTCHINSON J: (a) De l'acropathologie: maladie de Raynaud, et états similaires. Sem. Méd. 13: 109, 1893; (b) Inherited liability to Raynaud's phenomena, with great proneness to chilbains—gradual increase of liability to paroxysmal local asphyxia—acro-spacelus with sclerodermia—cheeks affected. Arch. Surg. 4: 312, 1893; (c) Acroscleroderma following Raynaud's phenomena. Clin. J. 7: 240, 1896. Google Scholar*54. BUSCHKE A: (a) Case presentation. Arch. Derm. Syph. 53: 383, 1900; (b) Über das Sklerödem und seine Beziehung zur Sklerodermie. Derm. Wschr. 70: 17, 1920. Google Scholar55. VALLEE BL: Scleredema: a systemic disease. New Engl. J. Med. 235: 207, 1946. CrossrefMedlineGoogle Scholar56. LEINWAND I: Generalized scleredema: report with autopsy findings. Ann. Intern. Med. 34: 226, 1951. LinkGoogle Scholar57. OSLER W: (a) The Principles and Practice of Medicine, D. Appleton and Company, New York, 1892, p. 993; (b) On diffuse scleroderma; with special reference to diagnosis and the use of thyroid-gland extract. J. Cutan. Genito-urin. Dis. 16: 49, 127, 1898. Google Scholar58. CHRISTIAN H: The Principles and Practice of Medicine (originally written by William Osler, M.D., F.R.C.P.), 16th ed., D. Appleton-Century Co., New York, 1947, p. 1145. Google Scholar*59. MATSUI S: Über die Pathologie und Pathogenese von Sklerodermia universalis. Mitt. Med. Fakult. Kaiserl. Univ. Tokyo 31: 55, 1924. Google Scholar*60. EHRMANNBRÜNAUER SSR: Sclerodermie, in Handbuch der Haut-und Geschlechtskrankheiten, vol. 8 (part 2), ed. by Jadassohn, J., J. Springer, Berlin, 1931, p. 717. Google Scholar61. DERCUM FX: (a) Scleroderma. J. Nerv. Ment. Dis. 21: 431, 1896; (b) On scleroderma and chronic rheumatoid arthritis. J. Nerv. Ment. Dis. 25: 703, 1898. CrossrefGoogle Scholar*62. ADRIANROEDERER CJ: Les arthropathies au cours de la sclérodermie. Ann. Derm. Syph. 1: 299, 341, 395, 1920. Google Scholar63. COLIEZ E: Du Sclérème des Adultes, Lefrançois, Paris, 1873, pp. 51-52. Google Scholar64. FINLAY DW: (a) Clinical notes. Sclerodermia. Brit. J. Dermat. 1: 339, 1889; (b) Abstracts of exceptional cases. Middlesex Hosp. Rep. (1889), London, 1891, p. 29. Google Scholar*65. DINKLER M: Zur Lehre von der Sklerodermia. Deutsch. Arch. Klin. Med. 48: 514, 1891. Google Scholar66. HOPPE-SEYLER G: Zwei Fälle von Sklerodermie. Deutsch. Arch. Klin. Med. 44: 581, 1889. Google Scholar67. VON NOTTHAFFT A: Neure Arbeiten und Ansichten über Sklerodermie. Zbl. Allg. Path. 9: 870, 1898. Google Scholar68. GETZOWA S: Cystic and compact pulmonary sclerosis in progressive scleroderma. Arch. Path. 40: 99, 1945. Google Scholar69. MURPHYKRAININGERSON JRPMJ: Scleroderma with pulmonary fibrosis. J. A. M. A. 116: 499, 1941. CrossrefGoogle Scholar70. LINENTHALTALKOV HR(a) : Pulmonary fibrosis in Raynaud's disease. New Engl. J. Med. 224: 682, 1941; (b) LINENTHAL, H.: Pulmonary complications in Raynaud's disease. New Engl. J. Med. 216: 188, 1937. CrossrefGoogle Scholar71. LLOYDTONKIN WERD: Pulmonary fibrosis in generalized scleroderma. Review of the literature and report of four further cases. Thorax 3: 241, 1948. CrossrefMedlineGoogle Scholar72. ZATUCHNICAMPBELLZARAFONETIS JWNCJ: Pulmonary fibrosis and terminal bronchiolar ("alveolar-cell") carcinoma in scleroderma. Cancer 6: 1147, 1953. CrossrefMedlineGoogle Scholar73. EHRMANN S: Über die Beziehung der Sklerodermie zu den autotoxischen Erythemen. Wien. Med. Wschr. 53: 1097, 1156, 1903. Google Scholar74. SCHMIDT R: Sklerodermie mit Dysphagie. Deutsch. Med. Wschr. 42: 1023, 1916. Google Scholar*75. RAKE G: On the pathology and pathogenesis of scleroderma. Bull. Johns Hopkins Hosp. 48: 212, 1931. Google Scholar76. KURÉYAMAGATATSUKADAHIYOSHI KKSJ: Passagestörung des Oesophagus bei Sklerodermie und Dystrophia musculorum progressiva. Klin. Wschr. 15: 516, 1936. CrossrefGoogle Scholar77. WEISSENBACHSTEWARTHOESLI RJWH: Les troubles fonctionnels oesophagiens et les lésions de l'oesophage dans la sclérodermie. Bull. Soc. Franç. Derm. Syph. 44: 1060, 1937. Google Scholar78. LINDSAYTEMPLETONROTHMAN JRFES: Lesion of the esophagus in generalized progressive scleroderma. J. A. M. A. 123: 745, 1943. CrossrefGoogle Scholar*79. WEISSSTEADWARRENBAILEY SEAJVOT: Scleroderma heart disease with a consideration of certain other visceral manifestations of scleroderma. Arch. Intern. Med. 71: 749, 1943. CrossrefGoogle Scholar*80. HALESCHATZKI CHR: Roentgenological appearance of gastrointestinal tract in scleroderma. Amer. J. Roentgenol. 51: 407, 1944. Google Scholar81. BEVANS M: Pathology of scleroderma, with special reference to changes in the gastrointestinal tract. Amer. J. Path. 21: 25, 1945. MedlineGoogle Scholar82. OLSENO'LEARYKIRKLIN AMPABR: Esophageal lesions associated with acrosclerosis and scleroderma. Arch. Intern. Med. 76: 189, 1945. CrossrefGoogle Scholar83. KRAUS EJ: Zur Pathogenese der diffusen Sklerodermie. Zugleich ein Beitrag zur Pathologie der Epithelkörperchen. Virchow. Arch. Path. Anat. 253: 710, 1924. CrossrefGoogle Scholar84. HEINE J: Über ein eigenartiges Krankheitsbild von diffuser Sklerosis der Haut und innerer Organe. Virchow. Arch. Path. Anat. 262: 351, 1926. CrossrefGoogle Scholar85. SNAPPERSEELYFALKFEDER IRSI: Osteomalacia in New York. Ann. Intern. Med. 41: 893, 1954. LinkGoogle Scholar86. ABRAMSCARNESEATON HLWHJ: Alimentary tract in disseminated scleroderma with emphasis on small bowel. Arch. Intern. Med. 94: 61, 1954. CrossrefGoogle Scholar87. ROSENTHAL FD: Small intestinal lesions with steatorrhea in diffuse systemic sclerosis (scleroderma). Gastroenterology 32: 332, 1957. CrossrefMedlineGoogle Scholar88. WESTPHAL : Zwei Fälle von Sclerodermie. Charité-Annalen (Berlin) 3: 341, 1876 (Berlin: A. Hirschwald, 1878). Google Scholar89. GITLOWSTEINER SS: Scleroderma with special reference to the blood chemistry. Report of a case. Arch. Derm. Syph. 9: 549, 1924. CrossrefGoogle Scholar90. BROCK WG: Dermatomyositis and diffuse scleroderma. Differential diagnosis and reports of cases. Arch. Derm. Syph. 30: 227, 1934. CrossrefGoogle Scholar91. AUSPITZ H: Ein Beitrag zur Lehre vom Haut-Sklerem der Erwachsenen. Wien. Med. Wschr. 13: 739, 755, 771, 788, 1863. Google Scholar*92. MASUGIYÄ-SHU. M: Die diffuse Sklerodermia und ihre Gefässveranderung. Virchow. Arch. Path. Anat. 302: 39, 1938. CrossrefGoogle Scholar93. TALBOTTGALLCONSOLAZIOCOOMBS JHEAWVFS: Dermatomyositis with scleroderma, calcinosis and renal endarteritis associated with focal cortical necrosis. Arch. Intern. Med. 63: 476, 1939. CrossrefGoogle Scholar*94. MOORESHEEHAN HCHL: The kidney of scleroderma. Lancet 1: 68, 1952. CrossrefMedlineGoogle Scholar95. BALL B: (a) Case presentation. Compte Rendu Séances Soc. Biol. 23: 43, 1871; (b) [Case presentation: ". . . un jeune homme atteint de sclerodactylie, avec tendance à l'envahissement et à la sclérodermie générale . . . , " 1874.] Bull. Mém Soc. Méd. Hôp. Paris 11: 96, 1875. Google Scholar96. NORDT J: Ueber das einfache Sklerom der Haut. Thesis, Giessen, 1861. Google Scholar97. SELLEI J: (a) Die Akrosklerosis (Sklerodaktylie) und deren Symptomen-komplex nebst neueren Untersuchungen bei Sklerodermie. Arch. Derm. Syph. 163: 343, 1931; (b) The diagnosis and treatment of scleroderma and acrosclerosis and some of their kindred diseases. Brit. J. Derm. 46: 523, 1934. CrossrefGoogle Scholar98. O'LEARYWAISMAN PAM: Acrosclerosis. Arch. Intern. Med. 47: 382, 1943. Google Scholar99. JABLOŃSKABUBNOWKIKASIAK SBB: Acrosclerosis: a disease sui generis or a variety of diffuse scleroderma? Brit. J. Derm. 71: 123, 1959. CrossrefMedlineGoogle Scholar100. ŠŤÁVA Z: The problem of the interrelation between diffuse generalized scleroderma, acrosclerosis, Raynaud's phenomenon and Raynaud's disease. Dermatologica 118: 1, 1959. CrossrefGoogle Scholar101. FARMERGIFFORDHINES RGRWEA: Prognostic significance of Raynaud's phenomenon and other clinical characteristics of systemic scleroderma. A study of 271 cases. Circulation 21: 1088, 1960. CrossrefMedlineGoogle Scholar*102. FOERSTER A: Zur pathologischen Anatomie des Scleroma der Haut bei Erwachsenen. Würzb. Med. Z. 2: 294, 1861. Google Scholar103. UNNA PG: The Histopathology of the Diseases of the Skin (1894), translated by Walker, N., The Macmillan Company, New York, 1896, p. 1100. Google Scholar*104. BANKS BM: Is there a common denominator in scleroderma, dermatomyositis, disseminated lupus erythematosus, the Libman-Sacks syndrome and polyarteritis nodosa? New Engl. J. Med. 225: 433, 1941. CrossrefGoogle Scholar*105. KLEMPERERPOLLACKBAEHR PADG: (a) Diffuse collagen disease. Acute disseminated lupus erythematosus and diffuse scleroderma. J. A. M. A. 119: 331, 1942; (b) The concept of collagen diseases. Amer. J. Path. 26: 505, 1950; (c) The significance of the intermediate substances of the connective tissue in human disease. Harvey Lect. 49: 100, 1953. CrossrefGoogle Scholar106. RODNAN GP A review of recent observations and current theories on the etiology and pathogenesis of progressive systemic sclerosis (diffuse scleroderma). To be published. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: GERALD P. RODNAN, M.D.; THOMAS G. BENEDEK, M.D.Affiliations: Pittsburgh, PennsylvaniaFrom the Department of Medicine, University of Pittsburgh School of Medicine, and the Veterans Administration Hospital, Pittsburgh, Pennsylvania.Requests for reprints should be addressed to Gerald P. Rodnan, M.D., University of Pittsburgh School of Medicine, Department of Medicine, Pittsburgh 13, Pennsylvania. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySystemic Scleroderma—Definition, Clinical Picture and Laboratory DiagnosticsFibrotic diseasesSystemic sclerosis: what's in a name?Scleroderma-specific autoantibodies embedded in immune complexes mediate endothelial damage: an early event in the pathogenesis of systemic sclerosisSystemic Sclerosis in ChildhoodHidebound bowel signHistorical Perspective of SclerodermaClinical Features and Treatment of SclerodermaScleroderma-related interstitial lung diseasePredictors of inpatient mortality in patients with systemic sclerosis: a case control studyBiomarkers in Scleroderma: Progressing from Association to Clinical UtilityDiffuse Systemic Sclerosis"United we Win", Communication is the Key for a Better Future in SclerodermaSystemic Sclerosis and the HeartScleroderma renal crisis and ovarian hyperstimulation syndrome related to the use of clomiphene in a patient with sclerodermaScleroderma renal crisis and ovarian hyperstimulation syndrome related to the use of clomiphene in a patient with sclerodermaDisease modification in systemic sclerosis: the search for the Holy GrailHistoria del compromiso cutáneo de la esclerosis sistémicaClinical Features and Treatment of SclerodermaHistorical PerspectiveSystemic Sclerosis in ChildhoodClinical features of systemic sclerosisINTRODUCTION TO THE STUDY OF RHEUMATIC DISEASES IN CHILDRENAdvances in Vascular MedicineSystemic Sclerosis and the Scleroderma-Spectrum DisordersScleroderma: it has been a long hard journeyExon-1 polymorphism of ctla-4 gene is not associated with systemic sclerosis in Iranian patientsRenal complications and scleroderma renal crisisSkin disease: a cardinal feature of systemic sclerosisSystemic Sclerosis Mortality in the United States: 1979–1998Turgenev's 'Living Relic': an Early Description of Scleroderma?Histopathological changes of cervical tissue in women with systemic sclerosisTHROMBOTIC THROMBOCYTOPENIC PURPURA IN A CASE OF SCLERODERMA RENAL CRISIS TREATED WITH TWICE-DAILY THERAPEUTIC PLASMA EXCHANGEMotor Activity of The Gallbladder in Systemic SclerosisSCLERODERMA AND RELATED CONDITIONSHistorical approach to sclerodermaSYSTEMIC SCLEROSISScleroderma and the kidneyThe lungs in systemic sclerosis (scleroderma): A review and new informationSystemic sclerodermaSystemic diseases and the detection of antinuclear and anticytoplasmic antibodies. An hystorical reviewScleroderma and scleroderma-like disordersThe cardiovascular manifestations of systemic sclerosis (scleroderma)Heart disease in sclerodermaSelective inhibition of excessive scleroderma fibroblast collagen production by lymphokines from normal human mononuclear cellsManagement of sclerodermal finger ulcersThe early history and nomenclature of scleroderma and of its differentiation from sclerema neonatorum and scleroedemaPrimary heart disease in systemic sclerosis (scleroderma): Advances in clinical and pathologic features, pathogenesis, and new therapeutic approachesForewordProgressive Systemic Sclerosis: Cardiac InvolvementProgressive Systemic Sclerosis: Pulmonary InvolvementHistory of SclerodermaGERALD P. RODNAN, M.D., THOMAS G. BENEDEK, M.D.Pulmonary vascular changes in sclerodermaSclerodermaBIBLIOGRAPHY OF SECONDARY SOURCES ON THE HISTORY OF DERMATOLOGY.Myocardial lesions of progressive systemic sclerosis. A cause of cardiac dysfunction.De Subitaneis MortibusThe Rheumatic Diseases in AdolescenceZur Morphologie, Biochemie und Funktion der Proteoglycane in der DermatologieSekundäre maligne Tumoren der Bronchien und LungenNeuromuscular Disorders of the EsophagusREFERENCESCurzio's Case of SclerodermaI. CAPUSAN, M.D.Surgical treatment of strictures of the esophagus in patients with sclerodermaVascular Disease in Progressive Systemic Sclerosis (Scleroderma)WALTER L. NORTON, M.D., F.A.C.P., JOHN M. NARDO, M.D.Esophageal motor abnormalities in scleroderma and related diseasesEntwicklungslinien der Sklerodermieforschung in der GegenwartMITRAL AND AORTIC VALVE DISEASE IN A PATIENT WITH SCLERODERMARheumatism and Arthritis Review of American and English Literature of Recent Years (Sixteenth Rheumatism Review)CHARLEY J. SMYTH, M.D., F.A.C.P., ROGER L. BLACK, M.D., CHARLES CHRISTIAN, M.D., MACK L. CLAYTON, M.D., F.A.C.S., DONALD F. HILL, M.D., F.A.C.P., JOSEPH LEE HOLLANDER, M.D., F.A.C.P., WILLIAM M. MIKKELSEN, M.D., F.A.C.P., MAX M. MONTGOMERY, M.D., F.A.C.P., CARL M. PEARSON, M.D., F.A.C.P., HUGH A. SMYTHE, M.D., F.R.C.P. (C), L. EMMERSON WARD, M.D., F.A.C.P., HOWARD J. WEINBERGER, M.D., F.A.C.P.A bibliography of the history of the rheumatic diseases, 1940–1962Scleroderma (progressive systemic sclerosis) 1 August 1962Volume 57, Issue 2_Part_1Page: 305-319KeywordsConnective tissueGastrointestinal tractHeartHospital medicineKidneysLibrariesLungsScleroderma ePublished: 1 December 2008 Issue Published: 1 August 1962 PDF downloadLoading ...