Nosocomial Cerebral Aspergillosis: A Report of 3 Cases
1996; Informa; Volume: 28; Issue: 3 Linguagem: Inglês
10.3109/00365549609027182
ISSN1651-1980
AutoresC Darras-Joly, Benoît Veber, Jean‐Pierre Bédos, Bertrand Gachot, B. Régnier, Michel Wolff,
Tópico(s)Infectious Diseases and Mycology
ResumoCerebral aspergillosis carries a mortality rate close to 100%, especially in immunocompromised patients. We describe 3 patients who contracted cerebral aspergillosis after neurosurgery, 2 of whom survived after exhaustive surgical treatment and medical treatment with high doses of amphotericin B (once liposomal), 5-fluorocytosine and itraconazole. We review the few non-fatal cases of cerebral aspergillosis reported. We consider that surgical excision must be complete and repeated if necessary, always in combination with medical treatment.
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