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Cutaneous granulomatous reaction to injectable hyaluronic acid gel: Another case

2007; Informa; Volume: 18; Issue: 1 Linguagem: Inglês

10.1080/09546630601121052

1471-1753

Federico Bardazzi, Alberto Ruffato, Angela Antonucci, Riccardo Balestri, Michela Tabanelli,

Surgical Sutures and Adhesives

AbstractWe report a case of a granulomatous reaction in the melolabial folds, occurring 10 days after treatment with Restylane®. The patient, who had previously been treated with the same product in the last 2 years without any adverse effect, developed an unusual early fibrotic reaction that we hypothesized related to hypersensitivity after repeated use. The lesions slowly disappeared with topical steroid therapy. An improved knowledge of the modality of these uncommon adverse effects is necessary to assess the long‐term safety and efficacy of this product.KeywordsGranulomatous reactionhyaluronic acidhypersensitivityside effectsskin fillers