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Autophagosomes, phagosomes, autolysosomes, phagolysosomes, autophagolysosomes… Wait, I’m confused

2014; Taylor & Francis; Volume: 10; Issue: 4 Linguagem: Inglês

10.4161/auto.28448

1554-8635

Daniel J. Klionsky, Eeva‐Liisa Eskelinen, Vojo Deretić,

Endoplasmic Reticulum Stress and Disease

When an autophagosome or an amphisome fuse with a lysosome, the resulting compartment is referred to as an autolysosome. Some people writing papers on the topic of autophagy use the terms "autolysosome" and "autophagolysosome" interchangeably. We contend that these words should be used to denote 2 different compartments, and that it is worthwhile maintaining this distinction—the autophagolysosome has a particular origin in the process of xenophagy that makes it distinct from an autolysosome.