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Artigo Acesso aberto Revisado por pares
BIBTEX RIS

Lipoxygenase metabolites of arachidonic acid as second messengers for presynaptic inhibition of Aplysia sensory cells

1987; Nature Portfolio; Volume: 328; Issue: 6125 Linguagem: Inglês

10.1038/328038a0

ISSN

1476-4687

Autores

Daniele Piomelli, Andrea Volterra, Nicholas Dale, Steven A. Siegelbaum, Eric R. Kandel, James H. Schwartz, Francesco Belardetti,

Tópico(s)

Neurobiology and Insect Physiology Research

Resumo

Biochemical and biophysical studies on Aplysia sensory neurons indicate that inhibitory responses to the molluscan peptide FMRFamide are mediated by lipoxygenase metabolites of arachidonic acid. These compounds are a new class of second messengers in neurons.

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