Treatment of Antibiotic-Associated Enterocolitis with Vancomycin
1981; Oxford University Press; Volume: 3; Issue: Supplement_2 Linguagem: Inglês
10.1093/clinids/3.supplement_2.s273
ISSN1537-6591
AutoresRobert Fekety, Joseph Silva, John R. Armstrong, María Alló, Robert A. Browne, John R. Ebright, Rodney Lusk, Gary D. Rifkin, R. Toshniwal,
Tópico(s)Bacterial Identification and Susceptibility Testing
ResumoStudies in humans and hamsters have shown that Clostridium difficile is the most important cause of antibiotic-associated colitis. A toxin produced by the organism is responsible for the disease and can be detected in the stools of patients. Proctosigmoidoscopy is the quickest, as well as the most accurate, way to establish the diagnosis. The organisms are very susceptible to vancomycin, which is highly effective in treatment of the disease and also remarkably free of serious adverse effects when given orally.
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