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BIBTEX RIS

Pd-Catalyzed C–H Fluorination with Nucleophilic Fluoride

2012; American Chemical Society; Volume: 14; Issue: 16 Linguagem: Inglês

10.1021/ol301739f

ISSN

1523-7060

Autores

Kate B. McMurtrey, Joy M. Racowski, Melanie S. Sanford,

Tópico(s)

Synthesis and Catalytic Reactions

Resumo

The palladium-catalyzed C-H fluorination of 8-methylquinoline derivatives with nucleophilic fluoride is reported. This transformation involves the use of AgF as the fluoride source in combination with a hypervalent iodine oxidant. Both the scope and mechanism of the reaction are discussed.

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