Asymmetric Transfer Hydrogenation of Ketimines Using Well-Defined Iron(II)-Based Precatalysts Containing a PNNP Ligand
2012; American Chemical Society; Volume: 14; Issue: 17 Linguagem: Inglês
10.1021/ol302079q
ISSN1523-7060
AutoresAlexandre A. Mikhailine, Mazharul I. Maishan, Robert H. Morris,
Tópico(s)Surface Chemistry and Catalysis
ResumoWell-defined iron(II)-based complexes containing PNNP ligands catalyze a highly enantioselective reduction of N-(diphenylphosphinoyl)- and N-(p-tolylsulphonyl)-ketimines. Under mild conditions and low catalyst loading, the ketimines are successfully reduced to the corresponding amines in enantiomeric excess ranging from 94 to 99%.
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