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Fixed Drug Eruption and Pseudoephedrine

1994; American College of Physicians; Volume: 120; Issue: 5 Linguagem: Inglês

10.7326/0003-4819-120-5-199403010-00031

1539-3704

Manfred Hauken,

Pharmacovigilance and Adverse Drug Reactions

Letters1 March 1994Fixed Drug Eruption and PseudoephedrineManfred Hauken, MDManfred Hauken, MDSterling-Winthrop, Inc.; New York, NY 10016Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-120-5-199403010-00031 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:A suspected adverse drug experience related to a pseudoephedrine-containing product was reported to us and shared some features with the patient described by Cavanah and Ballas [1], who had a pseudoephedrine reaction presenting as the toxic shock syndrome.A 41-year-old man presented with a history of four episodes of an unusual fixed drug eruption after using a pseudoephedrine-containing product over the preceding 19 years. The first two episodes occurred at 22 years of age when he developed intense pruritus of the fingers approximately 12 hours after the ingestion of pseudoephedrine tablets. This symptom was followed by severe ...References1. Cavanah DK, Ballas ZK. Pseudoephedrine reaction presenting as recurrent toxic shock syndrome. Ann Intern Med. 1993; 119:302-3. Google Scholar2. Thankappen TP, Zachariah J. Drug specific clinical pattern in fixed drug eruptions. Int J Dermatol. 1991; 30:867-70. Google Scholar3. Camisa C. Fixed drug eruption to pseudoephedrine. Cutis. 1988; 41: 339-40. Google Scholar4. Taylor BJ, Duffil MB. Recurrent pseudoscarlatina and allergy to pseudoephedrine hydrochloride. Br J Dermatol. 1988; 118:827-9. Google Scholar5. Andrews GC, Domonkos AN, Arnold HL, Odom RB. Andrew's Diseases of the Skin. Clinical Dermatology. Philadelphia: W.B. Saunders; 1982:975. Google Scholar Author, Article, and Disclosure InformationAffiliations: Sterling-Winthrop, Inc.; New York, NY 10016 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByIn search of an ideal drug for safer treatment of obesity: The false promise of pseudoephedrineNon-pigmenting fixed drug eruption with mixed features of acute generalized exanthematous pustulosis induced by pseudoephedrine: a case reportDrug ReactionsApproach to the Patient With Presumed CellulitisNonpigmenting solitary fixed drug eruption caused by a Chinese traditional herbal medicine, ma huang (Ephedra Hebra), mainly containing pseudoephedrine and ephedrinePigmented purpuric dermatosis due to pseudoephedrineNonpigmenting solitary fixed drug eruption caused by pseudoephedrine hydrochlorideHistopathoiogy of dermatitis due to pseudoephedrineStereoisomeric Cutaneous HypersensitivityNonpigmented fixed drug eruption from pseudoephedrinePseudoephedrine 1 March 1994Volume 120, Issue 5Page: 442KeywordsAdverse reactionsConnective tissue diseasesDesquamationDrugsInflammationLymphocytesPruritusSigns and symptomsSkin reactionToxic shock syndrome Issue Published: 1 March 1994 CopyrightCopyright © 1994 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...