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Immunocytochemical localization of GABA in neurons projecting to the ventrolateral nucleus of the solitary tract

1989; Elsevier BV; Volume: 494; Issue: 1 Linguagem: Inglês

10.1016/0006-8993(89)90153-4

1872-6240

Christine A. Livingston, Albert J. Berger,

Neuroendocrine regulation and behavior

To determine the origin of γ-aminobutyric acidergic (GABAergic) input to the ventrolateral solitary tract nucleus (vlnTS), we used a double-labeling procedure for retrogradely transported horseradish peroxidase (HRP) and the immunocytochemical localization of GABA. Following HRP injections into the vlnTS, double-labeled neurons were found within the Bo¨tzinger Complex. We conclude that these double-labeled cells are the inhibitory Bo¨tzinger neurons and that GABA is a likely transmitter in this respiratory nucleus.