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INTERSTITIAL-CELL TUMOR OF THE TESTIS WITH GYNECOMASTIA*

1958; Oxford University Press; Volume: 18; Issue: 8 Linguagem: Inglês

10.1210/jcem-18-8-834

1945-7197

Walter Herrmann, Fillmore Buckner, Arnold M. Baskin,

Toxin Mechanisms and Immunotoxins

An interstitial-cell tumor of the testis with estrogen activity is reported. Evidence for estrogen secretion was based on clinical grounds as well as on a study of steroid excretion. The function of both the tubular and the endocrine apparatus of the testis was apparently suppressed as a result of the production of estrogen by the tumor. There was a return to normal function after removal of the tumor. The literature on the subject is reviewed and discussed.